A case of renal clear cell carcinoma presenting with a metastatic lesion in the oropharynx

Masayuki Kitano, Ryusuke Hori, Tsuyoshi Kojima, Yusuke Okanoue, Shintaro Fujimura, Seiji Oyagi, Kazuhiko Shoji

Research output: Contribution to journalArticlepeer-review


Metastatic tumors involving the oral mucosa are rare, comprising 1 to 3% of all malignant oral neoplasms. Metastatic renal cell carcinoma invading the soft tissue of the oral cavity is extremely rare. Furthermore, metastatic renal cell carcinoma of the soft tissue of the oral cavity as the presenting feature is very rare. We report a case of metastatic renal cell carcinoma that initially presented to us with a tumor of the oropharynx. The patient was a 65-year-old man who visited our department complaining of discomfort in the throat. Fiberoptic endoscopic examination revealed a tumor on the dorsal aspect of the oropharyngeal soft palate. Tumor biopsy revealed no malignant findings. On the basis of the findings on contrast-enhanced computed tomography (CT), the tumor was suspected as a hemangioma and trans-oral tumor resection was performed. Postoperative histopathological examination revealed findings consistent with clear cell carcinoma. Further examinations revealed a tumor in the right kidney. Nephrectomy was performed and the tumor was diagnosed as a clear cell carcinoma. In patients presenting with oral tumors that do not show typical histopathological findings such as squamous cell carcinoma, whole-body examination is recommended considering the possibility of metastatic tumor.

Original languageEnglish
Pages (from-to)271-276
Number of pages6
JournalPractica Oto-Rhino-Laryngologica
Issue number4
Publication statusPublished - 2018
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Otorhinolaryngology


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