A case of sepsis and meningitis caused by probable travel-related Neisseria meningitidis serogroup B infection the first report of N. meningitidis ST-4893 in Japan

Asami Nakayama, Hideyuki Takahashi, Kiyofumi Ohkusu, Katsuo Yamanaka, Chiyo Shintani, Satoshi Hayakawa, Junichi Ishii, Haruo Watanabe

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Herein we present a case of Neisseria meningitidis-related sepsis and meningitis in a 60- year-old woman. The N. meningitidis strain was identified as serogroup B and sequence type (ST)-4893 by multilocus sequence typing (MLST). The patient in this case had visited France prior to development of symptoms. No meningococcal isolate belonging to ST-4893 has been identified in Japan previously, whereas an ST-4893 strain from France has been reported in the MLST database. These results strongly suggest that this case is likely to have been imported from France.


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