A case of solid-pseudopapillary neoplasm, focusing on contrast-enhanced endoscopic ultrasonography

Takuya Ishikawa, Akihiro Itoh, Hiroki Kawashima, Eizaburo Ohno, Hiroshi Matsubara, Masanao Nakamura, Ryoji Miyahara, Naoki Ohmiya, Hidemi Goto, Yoshiki Hirooka

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We used contrast-enhanced endoscopic ultrasonography (CE-EUS) to diagnose a case of solid-pseudopapillary neoplasm (SPN) in an adult man. A 58-year-old man was referred to our hospital because of a pancreatic mass found by positron emission tomography (PET) using 18F-fluorodeoxyglucose (FDG) during a medical checkup in 2009. Trans-abdominal ultrasonography revealed a 24-mm hypoechoic mass at the pancreatic tail with calcification inside. Multiphasic computed tomography (CT) showed a solid mass with delayed enhancement. EUS revealed a hypoechoic mass without lateral shadowing, and neither a septum nor cystic component was detected. CE-EUS using Sonazoid® showed a hypovascular mass compared with the surrounding pancreatic parenchyma, and the inside of the mass was enhanced like an alveolus nest, suggesting pseudopapillary change. Diagnosis of a solid-pseudopapillary neoplasm and a concomitant small neuroendocrine tumor was made by distal pancreatectomy.

Original languageEnglish
Pages (from-to)209-216
Number of pages8
JournalJournal of Medical Ultrasonics
Issue number4
Publication statusPublished - 01-10-2011
Externally publishedYes


All Science Journal Classification (ASJC) codes

  • Radiology Nuclear Medicine and imaging

Cite this

Ishikawa, T., Itoh, A., Kawashima, H., Ohno, E., Matsubara, H., Nakamura, M., Miyahara, R., Ohmiya, N., Goto, H., & Hirooka, Y. (2011). A case of solid-pseudopapillary neoplasm, focusing on contrast-enhanced endoscopic ultrasonography. Journal of Medical Ultrasonics, 38(4), 209-216. https://doi.org/10.1007/s10396-011-0313-z