A case of successful treatment of granulocyte colony-stimulating factor producing hepatocellular carcinoma accompanying type B hepatitis with tegafur-uracil

Takanori Ito, Kenji Okubo, Masaya Shiomi, Michihiko Narita, Kiyoshi Morita, Atsufumi Takeuchi, Hironobu Kanazawa, Junichi Shimizu, Tomoaki Takeyama, Kiyotaka Hashizume, Hiroaki Shibahara, Daisaku Nishimura, Naoyuki Katada, Yoshiaki Katano, Hidemi Goto

Research output: Contribution to journalArticlepeer-review

3 Citations (Scopus)

Abstract

A 37-year-old man underwent lobectomy of the right liver for granulocyte colony-stimulating factor (G-CSF) producing hepatocellular carcinoma accompanying type B hepatitis. Within two months after the surgery, lung metastases were revealed and administration of sorafenib was begun, however, the lung metastases continued to enlarge. Changing the patient's medication to tegafur-uracil provided remarkable reduction of the lung metastases. The patient is alive two years after diagnosis and receives outpatient chemotherapy. We concluded that this case is valuable with regard to the extreme rarity of G-CSF producing hepatocellular carcinoma and its successful treatment in this case.

Original languageEnglish
Pages (from-to)2088-2096
Number of pages9
JournalJournal of Japanese Society of Gastroenterology
Volume109
Issue number12
Publication statusPublished - 12-2012
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Gastroenterology

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