A rare case of ulcerative colitis with severe benign stricture in which abdominoperineal resection was performed is reported. A 60-year-old man with a 15-year-history of ulcerative colitis was examined for weight loss. The patient had been diagnosed with ulcerative colitis 15 years previously at another hospital. Barium enema, colonoscopy, computed tomography (CT), and magnetic resonance imaging (MRI) revealed stricture in the rectum and the sigmoid colon. Abdominoperineal resection was performed because the stricture could not be discriminated from a malignancy. The resected specimen showed thickening of its wall and narrowing of its lumen. Pathological examination revealed that fibrosis in the submucosal layer and thickening of the muscle layer had caused the stricture and that there was no evidence of malignancy. Benign stricture in ulcerative colitis is rare, and only 13 cases have been reported in Japan. It is often difficult to diagnose benign stricture, and surgery is performed. It is hoped the research will clarify the cause of benign stricture in ulcerative colitis and that preventive treatment will be parformed in the early stage.
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