A case report of intestinal tuberculosis diagnosed by double balloon enteroscopy and interferon-γ assay

Takayoshi Fujita, Takafumi Ando, Osamu Watanabe, Osamu Maeda, Kazuhiro Ishiguro, Hironao Takahashi, Daisuke Ishikawa, Masaaki Minami, Motofusa Hasegawa, Naoki Omiya, Yasumasa Niwa, Shigeo Nakamura, Hidemi Goto

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Abstract

A 58-year-old woman was admitted in June 2005 with a fever of unknown origin. She had right lower quadrant abdominal pain. CT scan showed a thickened distal ileum wall and mesenteric lymph node enlargement. The differential diagnosis included : Crohn's disease, intestinal tuberculosis, malignant lymphoma, and Yersinia enteritis. On double balloon enteroscopy (DBE), mucosal edema and multiple circular ulcers were found in the distal ileum. On biopsy, a dense infiltration of lymphoid cells and an epithelioid granuloma with Langhans giant cells were noted. The whole-blood interferon-γ assay done using the QuantifFERON ® -TB2 G test (QFT) was positive. Intestinal tuberculosis was diagnosed. The patient's symptoms improved after anti-tuberculous therapy with isoniazid, rifanpicin, pyrazinamide and ethambutol. DBE and QFT were useful for diagnosing small bowel tuberculosis.

Original languageEnglish
Pages (from-to)2846-2851
Number of pages6
JournalGASTROENTEROLOGICAL ENDOSCOPY
Volume49
Issue number11
Publication statusPublished - 01-11-2007
Externally publishedYes

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All Science Journal Classification (ASJC) codes

  • Radiology Nuclear Medicine and imaging
  • Gastroenterology

Cite this

Fujita, T., Ando, T., Watanabe, O., Maeda, O., Ishiguro, K., Takahashi, H., Ishikawa, D., Minami, M., Hasegawa, M., Omiya, N., Niwa, Y., Nakamura, S., & Goto, H. (2007). A case report of intestinal tuberculosis diagnosed by double balloon enteroscopy and interferon-γ assay. GASTROENTEROLOGICAL ENDOSCOPY, 49(11), 2846-2851.