A Clinical Study of 448 Patients with Laryngeal Cancer

Four hundred forty-eight patients with laryngeal cancer were treated in our department between 1973 and 1992. There were 114 supraglottic (25.4%),330 glottic (73.7%)and four subglottic tumors (0.9%). The male to female ratio was approximately 12: 1, and the mean age of patients was 63.4 years. According to the TNM classi fication of malignant tumors proposed by the UICC (1987), eight cases of supraglottic tumor (7.0%) were stage I, 29 (25.4%) stage, 26 (22.8%) stage M, and 51 (44.8%) stage IV. Fifteen cases of glottic tumor (4.6%) were stage 0,134 (40.5%) stage I, 99 (30.0%) stage II, 60 (18.2%) stage M, and 22 (6.7%) stage IV, One case of subglottic tumor (25.0%) was stage I, and three (75.0%) stage III. The early stage cases (stage I, II) were predominant in the glottic type, while advanced stage cases (stage III, IV) were predominant in the supraglottic type. In 58 cases of supraglottic tumor (50.9%), total laryngectomy was performed, and in 197 cases of glottic tumor (59.7%), radiotherapy was chosen as the initial treatment. Laryngeal function was preserved in approximately 65% of all cases. The 5-and 10-year survival rate in supraglottic tumor were 55.7% and 50.0%. In glottic tumor, 80.7% and 75.7%. In subglottic tumor, 100.0% and 100.0% respectively. The 5-and 10-year survival rate were 75.9% and 68.7% in the entire series.