A Dirofilaria immitis polyprotein up-regulates nitric oxide production

Hiroyuki Tezuka; Shinjiro Imai; Setsuko Tsukidate; Koichiro Fujita

doi:10.1128/IAI.70.9.5283-5286.2002

A Dirofilaria immitis polyprotein up-regulates nitric oxide production

Hiroyuki Tezuka, Shinjiro Imai, Setsuko Tsukidate, Koichiro Fujita

Research output: Contribution to journal › Article › peer-review

9 Citations (Scopus)

Abstract

We investigated the effect of recombinant Dirofilaria immitis polyprotein (rDiAg) on nitric oxide (NO) production by peritoneal macrophages,. rDiAg induced NO production by macrophages from wild-type and lipopolysaccharide-hyporesponsive C3H/HeJ, but not CD40^-/-, mice. These results suggest that CD40 is involved in rDiAg-driven NO production by murine macrophages.

Original language	English
Pages (from-to)	5283-5286
Number of pages	4
Journal	Infection and Immunity
Volume	70
Issue number	9
DOIs	https://doi.org/10.1128/IAI.70.9.5283-5286.2002
Publication status	Published - 09-2002
Externally published	Yes

All Science Journal Classification (ASJC) codes

Parasitology
Microbiology
Immunology
Infectious Diseases

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1128/IAI.70.9.5283-5286.2002

Cite this

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abstract = "We investigated the effect of recombinant Dirofilaria immitis polyprotein (rDiAg) on nitric oxide (NO) production by peritoneal macrophages,. rDiAg induced NO production by macrophages from wild-type and lipopolysaccharide-hyporesponsive C3H/HeJ, but not CD40-/-, mice. These results suggest that CD40 is involved in rDiAg-driven NO production by murine macrophages.",

author = "Hiroyuki Tezuka and Shinjiro Imai and Setsuko Tsukidate and Koichiro Fujita",

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AU - Tsukidate, Setsuko

AU - Fujita, Koichiro

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AB - We investigated the effect of recombinant Dirofilaria immitis polyprotein (rDiAg) on nitric oxide (NO) production by peritoneal macrophages,. rDiAg induced NO production by macrophages from wild-type and lipopolysaccharide-hyporesponsive C3H/HeJ, but not CD40-/-, mice. These results suggest that CD40 is involved in rDiAg-driven NO production by murine macrophages.

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ER -

A Dirofilaria immitis polyprotein up-regulates nitric oxide production

Abstract

All Science Journal Classification (ASJC) codes

UN SDGs

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