A highly sensitive and specific fdcd method for chirality analysis of naturally occurring pteridines

Ning Chen, Kazuhisa Ikemoto, Takashi Sugimoto, Shizuaki Murata, Hiroshi Ichinose, Toshiharu Nagatsu

Research output: Contribution to journalArticlepeer-review

5 Citations (Scopus)

Abstract

Absolute configurations of 6-(1-hydroxyalkyl)pterin derivatives are determined by fluorescence detected circular dichroism (FDCD) spectroscopy. This method is at least 10 times more sensitive than CD analysis and specific even existence of 10 times excess amounts of chiral sugars or nucleic acids.

Original languageEnglish
Pages (from-to)387-392
Number of pages6
JournalHeterocycles
Volume56
Issue number1-2
Publication statusPublished - 01-01-2002
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Analytical Chemistry
  • Pharmacology
  • Organic Chemistry

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