A mechanism of quinolinic acid formation by brain in inflammatory neurological disease

Attenuation of synthesis from l-tryptophan by 6-chlorotryptophan and 4-cworo-3-hydroxy anthranilate

Melvyn P. Heyes, Kuniaki Saito, Eugene O. Major, Sheldon Milstien, Sanford P. Markey, James H. Vickers

Research output: Contribution to journalArticle

148 Citations (Scopus)
Original languageEnglish
Pages (from-to)1425-1450
Number of pages26
JournalBrain
Volume116
Issue number6
DOIs
Publication statusPublished - 01-01-1993
Externally publishedYes

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3-Hydroxyanthranilic Acid
Biopterin
Tryptophan Oxygenase
Myelitis
Kynurenic Acid
Quinolinic Acid
Kynurenine
Neopterin
Poliomyelitis
Encephalitis
Macaca mulatta
Tryptophan
Fetus
Brain
anthranilic acid
6-chlorotryptophan
Attenuation
Neurological Disease
Animals

All Science Journal Classification (ASJC) codes

  • Clinical Neurology

Cite this

Heyes, Melvyn P. ; Saito, Kuniaki ; Major, Eugene O. ; Milstien, Sheldon ; Markey, Sanford P. ; Vickers, James H. / A mechanism of quinolinic acid formation by brain in inflammatory neurological disease : Attenuation of synthesis from l-tryptophan by 6-chlorotryptophan and 4-cworo-3-hydroxy anthranilate. In: Brain. 1993 ; Vol. 116, No. 6. pp. 1425-1450.
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A mechanism of quinolinic acid formation by brain in inflammatory neurological disease : Attenuation of synthesis from l-tryptophan by 6-chlorotryptophan and 4-cworo-3-hydroxy anthranilate. / Heyes, Melvyn P.; Saito, Kuniaki; Major, Eugene O.; Milstien, Sheldon; Markey, Sanford P.; Vickers, James H.

In: Brain, Vol. 116, No. 6, 01.01.1993, p. 1425-1450.

Research output: Contribution to journalArticle

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