TY - JOUR
T1 - A multicenter study on oncologic outcome of laparoscopic gastrectomy for early cancer in Japan
AU - Kitano, Seigo
AU - Shiraishi, Norio
AU - Uyama, Ichiro
AU - Sugihara, Kenichi
AU - Tanigawa, Nobuhiko
AU - Inomata, Masafumi
AU - Yasuda, Kazuhiro
AU - Ochiai, Masahiro
AU - Kojima, Kazuyuki
AU - Enomoto, Masayuki
AU - Yasuno, Masamichi
AU - Katai, Hitoshi
AU - Kudo, Shinei
AU - Sakuramoto, Shinichi
AU - Takiguchi, Shuji
AU - Monden, Morito
AU - Tanimura, Shinya
AU - Higashino, Masayuki
AU - Fukunaga, Yosuke
AU - Nagai, Yugo
AU - Noshiro, Hirokazu
AU - Hayashi, Ken
AU - Hayashi, Hideki
AU - Ochiai, Takenori
AU - Fukunaga, Tetsu
AU - Fukunaga, Masaki
AU - Matsuda, Minoru
AU - Hoshi, Tomokazu
AU - Kasai, Shinichi
AU - Yamakawa, Tatsuo
AU - Murata, Nobuo
AU - Yanaga, Katsuhiko
N1 - Copyright:
Copyright 2008 Elsevier B.V., All rights reserved.
PY - 2007/1
Y1 - 2007/1
N2 - BACKGROUND: Laparoscopic surgery for gastric cancer is technically feasible, but it is not widely accepted because it has not been evaluated from the standpoint of oncologic outcome. We conducted a retrospective, multicenter study of a large series of patients in Japan to evaluate the short- and long-term outcomes of laparoscopic gastrectomy for early gastric cancer (EGC). METHODS: The study group comprised 1294 patients who underwent laparoscopic gastrectomy during the period April 1994 through December 2003 in 16 participating surgical units (Japanese Laparoscopic Surgery Study Group). The short- and long-term outcomes of these patients were examined. RESULTS: Distal gastrectomy was performed in 1185 patients (91.5%), proximal gastrectomy in 54 (4.2%), and total gastrectomy in 55 (4.3%); all were performed laparoscopically. The morbidity and mortality rates associated with these operations were 14.8% and 0%, respectively. Histologically, 1212 patients (93.7%) had stage IA disease, 75 (5.8%) had stage IB disease, and 7 (0.5%) had stage II disease (the UICC staging). Cancer recurred in only 6 (0.6%) of 1294 patients treated curatively (median follow-up, 36 months; range, 13-113 months). The 5-year disease-free survival rate was 99.8% for stage IA disease, 98.7% for stage IB disease, and 85.7% for stage II disease. CONCLUSIONS: Although our findings may be considered preliminary, our data indicate that laparoscopic surgery for EGC yields good short- and long-term oncologic outcomes.
AB - BACKGROUND: Laparoscopic surgery for gastric cancer is technically feasible, but it is not widely accepted because it has not been evaluated from the standpoint of oncologic outcome. We conducted a retrospective, multicenter study of a large series of patients in Japan to evaluate the short- and long-term outcomes of laparoscopic gastrectomy for early gastric cancer (EGC). METHODS: The study group comprised 1294 patients who underwent laparoscopic gastrectomy during the period April 1994 through December 2003 in 16 participating surgical units (Japanese Laparoscopic Surgery Study Group). The short- and long-term outcomes of these patients were examined. RESULTS: Distal gastrectomy was performed in 1185 patients (91.5%), proximal gastrectomy in 54 (4.2%), and total gastrectomy in 55 (4.3%); all were performed laparoscopically. The morbidity and mortality rates associated with these operations were 14.8% and 0%, respectively. Histologically, 1212 patients (93.7%) had stage IA disease, 75 (5.8%) had stage IB disease, and 7 (0.5%) had stage II disease (the UICC staging). Cancer recurred in only 6 (0.6%) of 1294 patients treated curatively (median follow-up, 36 months; range, 13-113 months). The 5-year disease-free survival rate was 99.8% for stage IA disease, 98.7% for stage IB disease, and 85.7% for stage II disease. CONCLUSIONS: Although our findings may be considered preliminary, our data indicate that laparoscopic surgery for EGC yields good short- and long-term oncologic outcomes.
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U2 - 10.1097/01.sla.0000225364.03133.f8
DO - 10.1097/01.sla.0000225364.03133.f8
M3 - Article
C2 - 17197967
AN - SCOPUS:33845950721
VL - 245
SP - 68
EP - 72
JO - Annals of Surgery
JF - Annals of Surgery
SN - 0003-4932
IS - 1
ER -