A nested case-control study of stomach cancer in relation to green tea consumption in Japan

Y. Hoshiyama, T. Kawaguchi, Y. Miura, T. Mizoue, N. Tokui, H. Yatsuya, K. Sakata, T. Kondo, S. Kikuchi, H. Toyoshima, N. Hayakawa, A. Tamakoshi, Y. Ohno, T. Yoshimura

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39 Citations (Scopus)


To evaluate whether green tea consumption provides protection against stomach cancer, the relative risks (RRs) were calculated in the Japan Collaborative Study for Evaluation of Cancer Risk, sponsored by the Ministry of Health and Welfare (JACC Study). The study was based on 157 incident cases and 285 controls aged 40-79 years. Cox proportional hazards regression analysis was used to estimate the RRs for stomach cancer. It was found that green tea consumption had no protective effect against stomach cancer. After adjustment for age, smoking status, H. pylori infection, history of peptic ulcer, and family history of stomach cancer along with certain dietary elements, the risks associated with drinking one or two, three or four, five to nine, and 10 or more cups of green tea per day, relative to those of drinking less than one cup per day, were 1.3 (95% confidence interval (Cl): 0.6-2.8), 1.0 (95% Cl: 0.5-1.9), 0.8 (95% Cl: 0.4-1.6), and 1.2 (95% Cl: 0.6-2.5), respectively (P for trend = 0.899). We found no inverse association between green tea consumption and the risk of stomach cancer.

Original languageEnglish
Pages (from-to)135-138
Number of pages4
JournalBritish Journal of Cancer
Issue number1
Publication statusPublished - 12-01-2004

All Science Journal Classification (ASJC) codes

  • Oncology
  • Cancer Research


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