A new genotype of TT virus (TTV) infection among Colombian native Indians

Yasuhito Tanaka, Masashi Mizokami, Etsuro Orito, Tatsunori Nakano, Takanobu Kato, Xin Ding, Tomoyoshi Ohno, Ryuzo Ueda, Shunro Sonoda, Kazuo Tajima, Tomoyuki Miura, Masanori Hayami

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36 Citations (Scopus)

Abstract

Serum TTV DNA was assayed in 140 native Indians and 40 members of the general population in Colombia to determine the prevalence of TT virus (TTV) infection among Colombian native Indians. Of the 140 native Indians, 23 (16.4%) were positive for TTV DNA, compared to 4 (10.0%) of 40 from the general population (P = not significant). The prevalence of TTV DNA among native Indians was much higher than that of HBsAg and anti-HCV. Comparison of subjects with and without TTV DNA revealed no significant differences in all characteristics between the two groups. A phylogenetic tree, using the open reading frame 1 sequence (222 bp), indicated that the virus could be classified into four different genotypes, including three previously reported ones. The results show that TTV infection is common in Colombian native Indians without liver disease and also indicate the existence of a novel genotype of TTV.

Original languageEnglish
Pages (from-to)264-268
Number of pages5
JournalJournal of Medical Virology
Volume57
Issue number3
DOIs
Publication statusPublished - 15-02-1999
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Virology
  • Infectious Diseases

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    Tanaka, Y., Mizokami, M., Orito, E., Nakano, T., Kato, T., Ding, X., Ohno, T., Ueda, R., Sonoda, S., Tajima, K., Miura, T., & Hayami, M. (1999). A new genotype of TT virus (TTV) infection among Colombian native Indians. Journal of Medical Virology, 57(3), 264-268. https://doi.org/10.1002/(SICI)1096-9071(199903)57:3<264::AID-JMV9>3.0.CO;2-D