TY - JOUR
T1 - A new genotype of TT virus (TTV) infection among Colombian native Indians
AU - Tanaka, Yasuhito
AU - Mizokami, Masashi
AU - Orito, Etsuro
AU - Nakano, Tatsunori
AU - Kato, Takanobu
AU - Ding, Xin
AU - Ohno, Tomoyoshi
AU - Ueda, Ryuzo
AU - Sonoda, Shunro
AU - Tajima, Kazuo
AU - Miura, Tomoyuki
AU - Hayami, Masanori
PY - 1999
Y1 - 1999
N2 - Serum TTV DNA was assayed in 140 native Indians and 40 members of the general population in Colombia to determine the prevalence of TT virus (TTV) infection among Colombian native Indians. Of the 140 native Indians, 23 (16.4%) were positive for TTV DNA, compared to 4 (10.0%) of 40 from the general population (P = not significant). The prevalence of TTV DNA among native Indians was much higher than that of HBsAg and anti-HCV. Comparison of subjects with and without TTV DNA revealed no significant differences in all characteristics between the two groups. A phylogenetic tree, using the open reading frame 1 sequence (222 bp), indicated that the virus could be classified into four different genotypes, including three previously reported ones. The results show that TTV infection is common in Colombian native Indians without liver disease and also indicate the existence of a novel genotype of TTV.
AB - Serum TTV DNA was assayed in 140 native Indians and 40 members of the general population in Colombia to determine the prevalence of TT virus (TTV) infection among Colombian native Indians. Of the 140 native Indians, 23 (16.4%) were positive for TTV DNA, compared to 4 (10.0%) of 40 from the general population (P = not significant). The prevalence of TTV DNA among native Indians was much higher than that of HBsAg and anti-HCV. Comparison of subjects with and without TTV DNA revealed no significant differences in all characteristics between the two groups. A phylogenetic tree, using the open reading frame 1 sequence (222 bp), indicated that the virus could be classified into four different genotypes, including three previously reported ones. The results show that TTV infection is common in Colombian native Indians without liver disease and also indicate the existence of a novel genotype of TTV.
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U2 - 10.1002/(SICI)1096-9071(199903)57:3<264::AID-JMV9>3.0.CO;2-D
DO - 10.1002/(SICI)1096-9071(199903)57:3<264::AID-JMV9>3.0.CO;2-D
M3 - Article
C2 - 10022798
AN - SCOPUS:0032913402
SN - 0146-6615
VL - 57
SP - 264
EP - 268
JO - Journal of Medical Virology
JF - Journal of Medical Virology
IS - 3
ER -
