TY - JOUR
T1 - A new putative G-protein coupled receptor gene associated with the immune system of rainbow trout (Oncorhynchus mykiss)
AU - Kiryu, Ikunari
AU - Köllner, Bernd
AU - Kuroda, Akashi
AU - Ototake, Mitsuru
AU - Dijkstra, Johannes Martinus
PY - 2003/8
Y1 - 2003/8
N2 - A putative G-protein coupled receptor (GPCR) gene belonging to the rhodopsin-like family was detected in rainbow trout and designated LPSenhR-1. Only moderate homology (<35%) was present with known GPCRs. Semi-quantitative RT-PCR indicated that the gene was expressed predominantly in lymphoid tissues, with highest expression associated with cells of the monocyte/macrophage lineage. Expression was strongly up-regulated by injection with LPS but not by infection with infectious haematopoietic necrosis virus.
AB - A putative G-protein coupled receptor (GPCR) gene belonging to the rhodopsin-like family was detected in rainbow trout and designated LPSenhR-1. Only moderate homology (<35%) was present with known GPCRs. Semi-quantitative RT-PCR indicated that the gene was expressed predominantly in lymphoid tissues, with highest expression associated with cells of the monocyte/macrophage lineage. Expression was strongly up-regulated by injection with LPS but not by infection with infectious haematopoietic necrosis virus.
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U2 - 10.1016/S1050-4648(02)00143-2
DO - 10.1016/S1050-4648(02)00143-2
M3 - Article
C2 - 12834616
SN - 1050-4648
VL - 15
SP - 117
EP - 127
JO - Fish and Shellfish Immunology
JF - Fish and Shellfish Immunology
IS - 2
ER -