A new putative G-protein coupled receptor gene associated with the immune system of rainbow trout (Oncorhynchus mykiss)

Ikunari Kiryu, Bernd Köllner, Akashi Kuroda, Mitsuru Ototake, J・m Dijkstra

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

A putative G-protein coupled receptor (GPCR) gene belonging to the rhodopsin-like family was detected in rainbow trout and designated LPSenhR-1. Only moderate homology (<35%) was present with known GPCRs. Semi-quantitative RT-PCR indicated that the gene was expressed predominantly in lymphoid tissues, with highest expression associated with cells of the monocyte/macrophage lineage. Expression was strongly up-regulated by injection with LPS but not by infection with infectious haematopoietic necrosis virus.

Original languageEnglish
Pages (from-to)117-127
Number of pages11
JournalFish and Shellfish Immunology
Volume15
Issue number2
DOIs
Publication statusPublished - 01-01-2003

Fingerprint

Immune system
immune system
G-Protein-Coupled Receptors
rainbow
Oncorhynchus mykiss
Genes
Infectious hematopoietic necrosis virus
rhodopsin
protein
Rhodopsin
gene
Macrophages
homology
Viruses
monocytes
virus
macrophages
genes
reverse transcriptase polymerase chain reaction
Tissue

All Science Journal Classification (ASJC) codes

  • Environmental Chemistry
  • Aquatic Science

Cite this

Kiryu, Ikunari ; Köllner, Bernd ; Kuroda, Akashi ; Ototake, Mitsuru ; Dijkstra, J・m. / A new putative G-protein coupled receptor gene associated with the immune system of rainbow trout (Oncorhynchus mykiss). In: Fish and Shellfish Immunology. 2003 ; Vol. 15, No. 2. pp. 117-127.
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A new putative G-protein coupled receptor gene associated with the immune system of rainbow trout (Oncorhynchus mykiss). / Kiryu, Ikunari; Köllner, Bernd; Kuroda, Akashi; Ototake, Mitsuru; Dijkstra, J・m.

In: Fish and Shellfish Immunology, Vol. 15, No. 2, 01.01.2003, p. 117-127.

Research output: Contribution to journalArticle

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