A patient who sufferred pulmonary tuberculosis with syndrome of inappropriate secretion of antidiuretic hormone, after radiotherapy for pulmonary adenocarcinoma

Kashin Kobayashi, Takahiko Horiguchi, Hideharu Hata, Yasushi Sasaki, Masahiro Hirose, Mamoru Shiga, Rieko Kondo, Souichi Tachikawa

Research output: Contribution to journalArticlepeer-review

Abstract

A 62-year-old man presented in June 2006 with right thoracic pain, cough, and weight loss, which had persisted for 3 months. Chest X-ray showed a mass-like shadow in the right pulmonary apex, suggesting a stage IIIb adenocarcinoma which was confirmed by biopsy. We gave a total radiation dose of 60 Gy, after this which general malaise and weakness were noted. The results of endocrinological examinations suggested syndrome of inappropriate antidiuretic hormone secretion (SIADH). Thoracic CT showed ground-glass opacity (GGO) in both lungs, and we could not rule out pulmonary tuberculosis. A sputum was positive for acid-fast stain and PCR-Tb, suggesting that SIADH was associated with pulmonary tuberculosis. Water restriction, i.v. physiological saline, and antituberculosis therapy relieved hyponatremia and the symptoms.

Original languageEnglish
Pages (from-to)947-951
Number of pages5
JournalNihon Kokyūki Gakkai zasshi = the journal of the Japanese Respiratory Society
Volume45
Issue number12
Publication statusPublished - 12-2007
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Medicine(all)

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