TY - JOUR
T1 - A patient with esophageal cancer with bone metastasis who achieved pain relief with repetitive administration of strontium-89 chloride
AU - Maeda, Osamu
AU - Ando, Takafumi
AU - Ishiguro, Kazuhiro
AU - Watanabe, Osamu
AU - Miyahara, Ryoji
AU - Nakamura, Masanao
AU - Funasaka, Kohei
AU - Furukawa, Kazuhiro
AU - Ando, Yuichi
AU - Kato, Katsuhiko
AU - Goto, Hidemi
N1 - Publisher Copyright:
© 2014, Springer Japan.
PY - 2014/10/8
Y1 - 2014/10/8
N2 - A 75-year-old woman was diagnosed with esophageal cancer with difficulty in swallowing. She had a past history of rheumatoid arthritis, scleroderma, interstitial pneumonia, angina pectoris (with coronary artery bypass surgery) and arrhythmia (with pacemaker implantation). She refused surgery, and chemotherapy and radiotherapy were not performed because of the high risk accompanied with multiple comorbidities. She received proton therapy at another hospital and the primary lesion shrank. Bone metastasis in the thoracic vertebrae was diagnosed 10 months after diagnosis of esophageal cancer. Non-steroidal anti-inflammatory drugs and zoledronic acid were administered for back pain. Oxycodone was also administered but discontinued due to nausea. After strontium-89 (89Sr) chloride administration, her back pain was relieved. 89Sr was administered five times every 3 months, and the pain did not worsen until her death due to pneumonia 2 years after diagnosis of esophageal cancer. 89Sr was effective for pain from bone metastasis of esophageal cancer, and its repeated administration was safe.
AB - A 75-year-old woman was diagnosed with esophageal cancer with difficulty in swallowing. She had a past history of rheumatoid arthritis, scleroderma, interstitial pneumonia, angina pectoris (with coronary artery bypass surgery) and arrhythmia (with pacemaker implantation). She refused surgery, and chemotherapy and radiotherapy were not performed because of the high risk accompanied with multiple comorbidities. She received proton therapy at another hospital and the primary lesion shrank. Bone metastasis in the thoracic vertebrae was diagnosed 10 months after diagnosis of esophageal cancer. Non-steroidal anti-inflammatory drugs and zoledronic acid were administered for back pain. Oxycodone was also administered but discontinued due to nausea. After strontium-89 (89Sr) chloride administration, her back pain was relieved. 89Sr was administered five times every 3 months, and the pain did not worsen until her death due to pneumonia 2 years after diagnosis of esophageal cancer. 89Sr was effective for pain from bone metastasis of esophageal cancer, and its repeated administration was safe.
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U2 - 10.1007/s12328-014-0515-1
DO - 10.1007/s12328-014-0515-1
M3 - Article
C2 - 26184016
AN - SCOPUS:84919844442
SN - 1865-7257
VL - 7
SP - 387
EP - 391
JO - Clinical Journal of Gastroenterology
JF - Clinical Journal of Gastroenterology
IS - 5
ER -