A patient with thiamine deficiency exhibiting muscle edema suggested by MRI

Kenichiro Murate, Yasuaki Mizutani, Toshiki Maeda, Ryunosuke Nagao, Kouichi Kikuchi, Sayuri Shima, Yoshiki Niimi, Akihiro Ueda, Shinji Ito, Tatsuro Mutoh

Research output: Contribution to journalArticlepeer-review

3 Citations (Scopus)


Myalgia is sometimes observed in patients with thiamine-deficiency neuropathy. However, the detailed mechanism(s) underlying muscular manifestations have been poorly elucidated. We herein report a possible patient with thiamine-deficiency neuropathy exhibiting muscle weakness and myalgia in lower limbs. The patient exhibited abnormal muscle signal intensities on MRI corresponding to the site of myalgia. After thiamine replacement therapy, rapid improvement of clinical symptoms and abnormal MRI findings were observed. Muscle MRI findings in this case implicated the possible mechanism of myalgia observed in patients with thiamine deficiency neuropathy.

Original languageEnglish
Article number1083
JournalFrontiers in Neurology
Publication statusPublished - 01-12-2018

All Science Journal Classification (ASJC) codes

  • Neurology
  • Clinical Neurology


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