A rare case of primary rectal extranodal NK/T-cell lymphoma, nasal type

Takehiro Fujii, Hiroyuki Kato, Makoto Suzaki, Takashi Noguchi, Hiroshi Imaf

Research output: Contribution to journalArticlepeer-review

Abstract

A 78-year-old woman was admitted to our hospital with high fever and obvious melena. The serum level of soluble IL-2 receptor was markedly high (1,910 U/ml), and an irregular mass was found 4 cm from the anal margin on digital examination. Abdominal computed tomography demonstrated the circumferential wall thickening of the lower rectum with peritumoral inframmatory changes. Colorectal endoscopy showed an easily-bleeding tumor with ulcer formation at 4 cm from the anal margin. We made a diagnosis of malignant tumor, possibly malignant lymphoma, originating from the lower rectum. We performed abdominoperineal resection with D2 lymph node dissection. The final diagnosis was extranodal NK/T-cell lymphoma originating from the rectum, with positive CD8, EBER and TIA-1 antibody reaction. The patient received postoperative chemotherapy with DeVIC (carboplatin, etoposide, ifostamide and dexamethasone), but died due to disseminated intravascular coagulation syndrome following disease recurrence.

Original languageEnglish
Pages (from-to)1205-1211
Number of pages7
JournalJapanese Journal of Gastroenterological Surgery
Volume44
Issue number9
DOIs
Publication statusPublished - 2011

All Science Journal Classification (ASJC) codes

  • Surgery
  • Gastroenterology

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