TY - JOUR
T1 - A Retrospective Analysis of the Relationship Between the Result of BRCA1/2 Genetic Testing and Surgical Method Selection in Japan
AU - Registration Committee of the Japanese HBOC consortium
AU - Inuzuka, Mayuko
AU - Watanabe, Chie
AU - Yokoyama, Shiro
AU - Kuwayama, Takashi
AU - Akashi-Tanaka, Sadako
AU - Arai, Masami
AU - Nakamura, Seigo
AU - Enomoto, Takayuki
AU - Nomizu, Tadashi
AU - Sakurai, Akihiro
AU - Sekine, Masayuki
AU - Nomura, Hiroyuki
AU - Ohkawa, Megumi
AU - Yotsumoto, Junko
N1 - Funding Information:
The authors acknowledge the members of Registration Committee, Japanese HBOC Consortium; Seigo Nakamura, Takayuki Enomoto, Tadashi Nomizu, Akihiro Sakurai, Masayuki Sekine, Hiroyuki Nomura, Megumi Ohkawa, Junko Yotsumoto, Chie Watanabe, and Shiro Yokoyama. The authors also acknowledge the 69 participating facilities of the nationwide registration projects; Showa Medical University Hospital, St. Luke's Hospital, Cancer Institute Hospital, Hoshi General Hospital, Shikoku Cancer Center, Hokkaido Cancer Center, Sapporo Medical Center, Niigata University Faculty of Medicine, Keio University, Kitano Hospital, Kochi University Faculty of Medicine, Tawara IVF Clinic, Kochi Medical Center, Nagoya University Hospital, St. Marianna University School of Medicine, Asahikawa Medical University, Aichi Cancer Center Hospital, Saku Medical Center, Tsukuba Medical University Hospital, Yokohama City University Hospital, Fujita Medical University Hospital, Ehime University Hospital, Gunma Prefectural Cancer Center, Nagasaki University Hospital, Shinshu University Hospital, Juntendo University Hospital, Kitazato University Hospital, Aichi Cancer Center Aichi Hospital, Okayama University Hospital, Saitama Medical University International Medical Center, Tokyo Medical Center, Tokyo Metropolitan Komagome Hospital, Japanese Red Cross Ishinomaki Hospital, Nagoya City University Hospital, Kawasaki Medical School Hospital, Yamanashi Prefectural Central Hospital, Nara Medical University Hospital, Kanagawa Cancer Center, Shiga Medical University, Shizuoka Cancer Center, Gifu University Hospital, Hiroshima Prefectural Hospital, Niigata Cancer Center Hospital, Japanese Red Cross Nagoya Daiichi Hospital, Tottori University Hospital, Kansai Rosai Hospital, Kokura Medical Center, Nippon Medical School Musashi Kosugi Hospital, Kansai Medical University Hospital, Sagara Hospital Breast Center, Chiba University Hospital, Ibaraki Prefectural Hospital, Fukui University Hospital, Hokkaido University Hospital, Saitama Medical Center, Osaka University, Japanese Red Cross Yamaguchi Hospital, Kyoto University Hospital, Konan Kosei Hospital, Japanese Red Cross Medical Center, Shonan Memorial Hospital, Shizuoka General Hospital, Hiroshima University Hospital, National Hospital Organization Kyoto Medical Center, Shiroyama Hospital, Saitama Cancer Center, National Hospital Organization Osaka National Hospital, Kitakyushu Municipal Medical Center, Iwate Medical University, and Tokuyama Central Hospital.
PY - 2021/2
Y1 - 2021/2
N2 - This study examined the relationship between BRCA1/2 genetic testing results and surgical method selection in patients with primary unilateral breast cancer in Japan. Compared with those without a mutation, patients with mutations tended to choose mastectomy. Additionally, all patients who underwent contralateral risk-reducing mastectomy were diagnosed with breast cancer before the age of 50 years.
AB - This study examined the relationship between BRCA1/2 genetic testing results and surgical method selection in patients with primary unilateral breast cancer in Japan. Compared with those without a mutation, patients with mutations tended to choose mastectomy. Additionally, all patients who underwent contralateral risk-reducing mastectomy were diagnosed with breast cancer before the age of 50 years.
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U2 - 10.1016/j.clbc.2020.08.004
DO - 10.1016/j.clbc.2020.08.004
M3 - Article
AN - SCOPUS:85090746556
VL - 21
SP - e48-e52
JO - Clinical Breast Cancer
JF - Clinical Breast Cancer
SN - 1526-8209
IS - 1
ER -