TY - JOUR
T1 - A retrospective cohort study on the association between poor sleep quality in junior high school students and high hemoglobin A1c level in early adults with higher body mass index values
AU - Kasahara, Tomoko
AU - Tsujiguchi, Hiromasa
AU - Takeshita, Yumie
AU - Hara, Akinori
AU - Suzuki, Keita
AU - Narukawa, Nobuhiko
AU - Hayashi, Koichiro
AU - Miyagi, Masateru
AU - Asai, Atsushi
AU - Yamada, Yohei
AU - Nakamura, Haruki
AU - Suzuki, Fumihiko
AU - Pham, Kim Oanh
AU - Hamagishi, Toshio
AU - Nakamura, Masaharu
AU - Shibata, Aki
AU - Shimizu, Yukari
AU - Nguyen, Thao Thi Thu
AU - Miyagi, Sakae
AU - Kambayashi, Yasuhiro
AU - Kannon, Takayuki
AU - Tajima, Atsushi
AU - Tsuboi, Hirohito
AU - Konoshita, Tadashi
AU - Takamura, Toshinari
AU - Nakamura, Hiroyuki
N1 - Funding Information:
We would like to express our deep gratitude to junior high school staff in Shika town who co-operated with this research, the commercial and industrial workers of Togi in Shika town, Shika Town Medical Health staff, and staff at the Graduate School of Advanced Preventive Medical Sciences, Kanazawa University Graduate School of Medicine. The authors declare that this manuscript is original, has not been published before, and is not currently being considered for publication elsewhere.
Funding Information:
T.K (Tomoko Kasahara). Y.T. and T.T conceptualized the study. T.K (Tomoko Kasahara) curated the date. T.K (Tomoko Kasahara) formally analyzed the data. H.N (Hiroyuki Nakamura) received educational and research funds for environmental ecology and public health, funded by the Education and Research Fund, for this study. T.T and H.N (Hiroyuki Nakamura) supported T.K (Tomoko Kasahara) and supervised the analysis of the findings of this work. T.K (Tomoko Kasahara) and H.T (Hiromasa Tsujiguti) conducted the investigation. T.K (Tomoko Kasahara), Y.T, T.T, H.T (Hiromasa Tsujiguti), and H.N (Hiroyuki Nakamura) designed the study method. T.K (Tomoko Kasahara), Y.T, H.T (Hiromasa Tsujiguti), and T.T, H.N (Hiroyuki Nakamura) administered this project. T.T and H.N (Hiroyuki Nakamura) verified the results. T.K (Tomoko Kasahara) wrote the original draft of the manuscript. All authors discussed the results and contributed to the final manuscript. All authors have read and approved the final manuscript.
Publisher Copyright:
© 2022, The Author(s).
PY - 2022/12
Y1 - 2022/12
N2 - Background: Few epidemiological studies have been performed to clarify the association between glucose metabolism disorders in early adults (20 years old) and physiological and environmental factors, including body mass index (BMI) in junior high school days. Therefore, we examined the association between hemoglobin A1c (HbA1c) level and body size (BMI) in early adulthood and lifestyles, including sleep habits and BMI in junior high school days in Shika town, a small town in Japan, by conducting a retrospective cohort study. Methods: We examined the HbA1c levels and body size (BMI) of 99 early adults who turned 20 years old between 2016 and 2020 and were residing in Shika town, Ishikawa Prefecture. We obtained the information on lifestyles and living environment factors, including BMI, from a questionnaire survey conducted among the subjects during their junior high school days (13–15 years old) from 2009 to 2013. Results: No correlations were observed between the HbA1c levels and the BMI values of the early adults. A two-way analysis of covariance (with the HbA1c levels and BMI values of the early adults as main factors) of the body size and lifestyle habits of the junior high school students revealed that “sleep quality in junior high school” was significantly poorer in the high HbA1c group than in the low HbA1c group in the early adults with high BMI values only. This result was also supported by the logistic regression analysis result. Conclusions: The present results indicate that poor sleep quality in junior high school was associated with the high HbA1c levels of the early adults with higher BMI values, which suggests that good sleep quality in junior high school prevents the development of hyperglycemia. However, the present study did not find any relationship between early-adult BMI and HbA1c level.
AB - Background: Few epidemiological studies have been performed to clarify the association between glucose metabolism disorders in early adults (20 years old) and physiological and environmental factors, including body mass index (BMI) in junior high school days. Therefore, we examined the association between hemoglobin A1c (HbA1c) level and body size (BMI) in early adulthood and lifestyles, including sleep habits and BMI in junior high school days in Shika town, a small town in Japan, by conducting a retrospective cohort study. Methods: We examined the HbA1c levels and body size (BMI) of 99 early adults who turned 20 years old between 2016 and 2020 and were residing in Shika town, Ishikawa Prefecture. We obtained the information on lifestyles and living environment factors, including BMI, from a questionnaire survey conducted among the subjects during their junior high school days (13–15 years old) from 2009 to 2013. Results: No correlations were observed between the HbA1c levels and the BMI values of the early adults. A two-way analysis of covariance (with the HbA1c levels and BMI values of the early adults as main factors) of the body size and lifestyle habits of the junior high school students revealed that “sleep quality in junior high school” was significantly poorer in the high HbA1c group than in the low HbA1c group in the early adults with high BMI values only. This result was also supported by the logistic regression analysis result. Conclusions: The present results indicate that poor sleep quality in junior high school was associated with the high HbA1c levels of the early adults with higher BMI values, which suggests that good sleep quality in junior high school prevents the development of hyperglycemia. However, the present study did not find any relationship between early-adult BMI and HbA1c level.
UR - http://www.scopus.com/inward/record.url?scp=85124679440&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85124679440&partnerID=8YFLogxK
U2 - 10.1186/s12902-022-00951-6
DO - 10.1186/s12902-022-00951-6
M3 - Article
C2 - 35164727
AN - SCOPUS:85124679440
VL - 22
JO - BMC Endocrine Disorders
JF - BMC Endocrine Disorders
SN - 1472-6823
IS - 1
M1 - 40
ER -