A Simple Technique to Improve Contractile Effect of Cold Plasma Jet on Acute Mouse Wound by Dropping Water

Nasruddin, Yukari Nakajima, Kanae Mukai, Emi Komatsu, Heni Setyowati Esti Rahayu, Muhammad Nur, Tatsuo Ishijima, Hiroshi Enomoto, Yoshihiko Uesugi, Junko Sugama, Toshio Nakatani

Research output: Contribution to journalArticlepeer-review

16 Citations (Scopus)

Abstract

A simple technique is tested to improve the contractile effect of a cold plasma jet on acute wounds of mice. Distilled water on the order of microliters is dropped onto wounds before treatment. To assess the fate of the water, an infrared thermal imager is applied. To evaluate the healing effect, macroscopic and immunohistological studies are conducted. Regarding the wound contractile effect, we show that combination treatment of plasma with dropped water seemed to have a greater effect than plasma treatment alone. Plasma may modify the wound surface through such water, chemically and physically. The histological stiffness of the wound surface during maturation and remodeling, however, may also influence the fate of the water during treatment.

Original languageEnglish
Pages (from-to)1128-1138
Number of pages11
JournalPlasma Processes and Polymers
Volume12
Issue number10
DOIs
Publication statusPublished - 10-2015
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Condensed Matter Physics
  • Polymers and Plastics

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