A study of DNA ploidy pattern, proliferation index and PCNA in duodenal carcinoma

Hiroki Imazu; Masao Kasahara; Kenji Shirono; Kenya Takeshita; Motohiro Niwa; Masamoto Murakami; Keisuke Minami; Yuji Mimoto; Kazuhiro Tashiro; Makoto Kuroda; Yoshikazu Mizoguchi; Yoshinobu Horibe; Kazuf Umi Arai; Masashi Suganuma

doi:10.11405/nisshoshi1964.89.1499

A study of DNA ploidy pattern, proliferation index and PCNA in duodenal carcinoma

Hiroki Imazu
, Masao Kasahara
, Kenji Shirono
, Kenya Takeshita
, Motohiro Niwa
, Masamoto Murakami
, Keisuke Minami
, Yuji Mimoto
, Kazuhiro Tashiro
, Makoto Kuroda
, Yoshikazu Mizoguchi
, Yoshinobu Horibe
, Kazuf Umi Arai
, Masashi Suganuma

Diagnostic pathology

Research output: Contribution to journal › Article › peer-review

5 Citations (Scopus)

Abstract

12 cases of duodenal carcinoma were studied for nuclear DNA ploidy patterns, the proliferation index (PI), proliferating cell nuclear antigen (PCNA) positive score (1=0∼25%, 2=26∼50%, 3=51∼75%, 4=76∼100%) and PCNA positive rate. DNA aneuploidy was observed in 9 cases (75%) and PCNA staining was positive in 11 cases (91.6%). DNA ploidy patterns, PI, PCNA positive scores and positive rates were not related to each other. No relationship DNA ploidy patterns for PCNA positive scores and PCNA positive rates could be found. The relationship between PI and PCNA positive score was found not to be significant (P<0.10). PI was revealed to correlate significantly (P<0.05) to PCNA positive rate.

Original language	English
Pages (from-to)	1499-1505
Number of pages	7
Journal	nippon shokakibyo gakkai zasshi
Volume	89
Issue number	8
DOIs	https://doi.org/10.11405/nisshoshi1964.89.1499
Publication status	Published - 1992

All Science Journal Classification (ASJC) codes

Gastroenterology

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10.11405/nisshoshi1964.89.1499

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title = "A study of DNA ploidy pattern, proliferation index and PCNA in duodenal carcinoma",

abstract = "12 cases of duodenal carcinoma were studied for nuclear DNA ploidy patterns, the proliferation index (PI), proliferating cell nuclear antigen (PCNA) positive score (1=0∼25\%, 2=26∼50\%, 3=51∼75\%, 4=76∼100\%) and PCNA positive rate. DNA aneuploidy was observed in 9 cases (75\%) and PCNA staining was positive in 11 cases (91.6\%). DNA ploidy patterns, PI, PCNA positive scores and positive rates were not related to each other. No relationship DNA ploidy patterns for PCNA positive scores and PCNA positive rates could be found. The relationship between PI and PCNA positive score was found not to be significant (P<0.10). PI was revealed to correlate significantly (P<0.05) to PCNA positive rate.",

author = "Hiroki Imazu and Masao Kasahara and Kenji Shirono and Kenya Takeshita and Motohiro Niwa and Masamoto Murakami and Keisuke Minami and Yuji Mimoto and Kazuhiro Tashiro and Makoto Kuroda and Yoshikazu Mizoguchi and Yoshinobu Horibe and Arai, \{Kazuf Umi\} and Masashi Suganuma",

year = "1992",

doi = "10.11405/nisshoshi1964.89.1499",

language = "English",

volume = "89",

pages = "1499--1505",

journal = "nippon shokakibyo gakkai zasshi",

issn = "0446-6586",

publisher = "Japanese Society of Gastroenterology",

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TY - JOUR

T1 - A study of DNA ploidy pattern, proliferation index and PCNA in duodenal carcinoma

AU - Imazu, Hiroki

AU - Kasahara, Masao

AU - Shirono, Kenji

AU - Takeshita, Kenya

AU - Niwa, Motohiro

AU - Murakami, Masamoto

AU - Minami, Keisuke

AU - Mimoto, Yuji

AU - Tashiro, Kazuhiro

AU - Kuroda, Makoto

AU - Mizoguchi, Yoshikazu

AU - Horibe, Yoshinobu

AU - Arai, Kazuf Umi

AU - Suganuma, Masashi

PY - 1992

Y1 - 1992

N2 - 12 cases of duodenal carcinoma were studied for nuclear DNA ploidy patterns, the proliferation index (PI), proliferating cell nuclear antigen (PCNA) positive score (1=0∼25%, 2=26∼50%, 3=51∼75%, 4=76∼100%) and PCNA positive rate. DNA aneuploidy was observed in 9 cases (75%) and PCNA staining was positive in 11 cases (91.6%). DNA ploidy patterns, PI, PCNA positive scores and positive rates were not related to each other. No relationship DNA ploidy patterns for PCNA positive scores and PCNA positive rates could be found. The relationship between PI and PCNA positive score was found not to be significant (P<0.10). PI was revealed to correlate significantly (P<0.05) to PCNA positive rate.

AB - 12 cases of duodenal carcinoma were studied for nuclear DNA ploidy patterns, the proliferation index (PI), proliferating cell nuclear antigen (PCNA) positive score (1=0∼25%, 2=26∼50%, 3=51∼75%, 4=76∼100%) and PCNA positive rate. DNA aneuploidy was observed in 9 cases (75%) and PCNA staining was positive in 11 cases (91.6%). DNA ploidy patterns, PI, PCNA positive scores and positive rates were not related to each other. No relationship DNA ploidy patterns for PCNA positive scores and PCNA positive rates could be found. The relationship between PI and PCNA positive score was found not to be significant (P<0.10). PI was revealed to correlate significantly (P<0.05) to PCNA positive rate.

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U2 - 10.11405/nisshoshi1964.89.1499

DO - 10.11405/nisshoshi1964.89.1499

M3 - Article

C2 - 1357216

AN - SCOPUS:0026664753

SN - 0446-6586

VL - 89

SP - 1499

EP - 1505

JO - nippon shokakibyo gakkai zasshi

JF - nippon shokakibyo gakkai zasshi

IS - 8

ER -

A study of DNA ploidy pattern, proliferation index and PCNA in duodenal carcinoma

Abstract

All Science Journal Classification (ASJC) codes

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