A tomato-rich diet is related to depressive symptoms among an elderly population aged 70 years and over

A population-based, cross-sectional analysis

Kaijun Niu, Hui Guo, Masako Kakizaki, Yufei Cui, Kaori Ohmori-Matsuda, Lei Guan, Atsushi Hozawa, Shinichi Kuriyama, Toru Tsuboya, Takashi Ohrui, Katsutoshi Furukawa, Hiroyuki Arai, Ichiro Tsuji, Ryoichi Nagatomi

Research output: Contribution to journalArticle

18 Citations (Scopus)

Abstract

Background: Enhanced oxidative stress or defective anti-oxidant defenses are related to the pathogenesis of depressive symptoms. Lycopene is the most powerful antioxidant amongst the carotenoids. The aim of this study was to investigate the relationship between different vegetables, including tomatoes/tomato products (a major source of lycopene), and depressive symptoms in a community-based elderly population. Methods: We analyzed a cross-sectional survey including 986 community-dwelling elderly Japanese individuals aged 70 years and older. Dietary intake was assessed using a valid self-administered diet-history questionnaire, and depressive symptoms were evaluated using the 30-item Geriatric Depression Scale with 2 cut-off points: 11 (mild and severe) and 14 (severe) or use of anti-depressive agents. Results: The prevalence of mild and severe and severe depressive symptoms was 34.9% and 20.2%, respectively. After adjustments for potentially confounding factors, the odds ratios of having mild and severe depressive symptoms by increasing levels of tomatoes/tomato products were 1.00, 0.54, and 0.48 (p for trend <0.01). Similar relationships were also observed in the case of severe depressive symptoms. In contrast, no relationship was observed between intake of other kinds of vegetables and depressive symptoms. Limitations: This is a cross-sectional study, and not for making a clinical diagnosis of depressive episodes. Conclusions: This study demonstrated that a tomato-rich diet is independently related to lower prevalence of depressive symptoms. These results suggest that a tomato-rich diet may have a beneficial effect on the prevention of depressive symptoms. Further studies are needed to confirm these findings.

Original languageEnglish
Pages (from-to)165-170
Number of pages6
JournalJournal of Affective Disorders
Volume144
Issue number1-2
DOIs
Publication statusPublished - 10-01-2013

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Lycopersicon esculentum
Cross-Sectional Studies
Depression
Diet
Population
Vegetables
Independent Living
Carotenoids
Oxidants
Geriatrics
Oxidative Stress
Antioxidants
History
Odds Ratio

All Science Journal Classification (ASJC) codes

  • Clinical Psychology
  • Psychiatry and Mental health

Cite this

Niu, Kaijun ; Guo, Hui ; Kakizaki, Masako ; Cui, Yufei ; Ohmori-Matsuda, Kaori ; Guan, Lei ; Hozawa, Atsushi ; Kuriyama, Shinichi ; Tsuboya, Toru ; Ohrui, Takashi ; Furukawa, Katsutoshi ; Arai, Hiroyuki ; Tsuji, Ichiro ; Nagatomi, Ryoichi. / A tomato-rich diet is related to depressive symptoms among an elderly population aged 70 years and over : A population-based, cross-sectional analysis. In: Journal of Affective Disorders. 2013 ; Vol. 144, No. 1-2. pp. 165-170.
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title = "A tomato-rich diet is related to depressive symptoms among an elderly population aged 70 years and over: A population-based, cross-sectional analysis",
abstract = "Background: Enhanced oxidative stress or defective anti-oxidant defenses are related to the pathogenesis of depressive symptoms. Lycopene is the most powerful antioxidant amongst the carotenoids. The aim of this study was to investigate the relationship between different vegetables, including tomatoes/tomato products (a major source of lycopene), and depressive symptoms in a community-based elderly population. Methods: We analyzed a cross-sectional survey including 986 community-dwelling elderly Japanese individuals aged 70 years and older. Dietary intake was assessed using a valid self-administered diet-history questionnaire, and depressive symptoms were evaluated using the 30-item Geriatric Depression Scale with 2 cut-off points: 11 (mild and severe) and 14 (severe) or use of anti-depressive agents. Results: The prevalence of mild and severe and severe depressive symptoms was 34.9{\%} and 20.2{\%}, respectively. After adjustments for potentially confounding factors, the odds ratios of having mild and severe depressive symptoms by increasing levels of tomatoes/tomato products were 1.00, 0.54, and 0.48 (p for trend <0.01). Similar relationships were also observed in the case of severe depressive symptoms. In contrast, no relationship was observed between intake of other kinds of vegetables and depressive symptoms. Limitations: This is a cross-sectional study, and not for making a clinical diagnosis of depressive episodes. Conclusions: This study demonstrated that a tomato-rich diet is independently related to lower prevalence of depressive symptoms. These results suggest that a tomato-rich diet may have a beneficial effect on the prevention of depressive symptoms. Further studies are needed to confirm these findings.",
author = "Kaijun Niu and Hui Guo and Masako Kakizaki and Yufei Cui and Kaori Ohmori-Matsuda and Lei Guan and Atsushi Hozawa and Shinichi Kuriyama and Toru Tsuboya and Takashi Ohrui and Katsutoshi Furukawa and Hiroyuki Arai and Ichiro Tsuji and Ryoichi Nagatomi",
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Niu, K, Guo, H, Kakizaki, M, Cui, Y, Ohmori-Matsuda, K, Guan, L, Hozawa, A, Kuriyama, S, Tsuboya, T, Ohrui, T, Furukawa, K, Arai, H, Tsuji, I & Nagatomi, R 2013, 'A tomato-rich diet is related to depressive symptoms among an elderly population aged 70 years and over: A population-based, cross-sectional analysis', Journal of Affective Disorders, vol. 144, no. 1-2, pp. 165-170. https://doi.org/10.1016/j.jad.2012.04.040

A tomato-rich diet is related to depressive symptoms among an elderly population aged 70 years and over : A population-based, cross-sectional analysis. / Niu, Kaijun; Guo, Hui; Kakizaki, Masako; Cui, Yufei; Ohmori-Matsuda, Kaori; Guan, Lei; Hozawa, Atsushi; Kuriyama, Shinichi; Tsuboya, Toru; Ohrui, Takashi; Furukawa, Katsutoshi; Arai, Hiroyuki; Tsuji, Ichiro; Nagatomi, Ryoichi.

In: Journal of Affective Disorders, Vol. 144, No. 1-2, 10.01.2013, p. 165-170.

Research output: Contribution to journalArticle

TY - JOUR

T1 - A tomato-rich diet is related to depressive symptoms among an elderly population aged 70 years and over

T2 - A population-based, cross-sectional analysis

AU - Niu, Kaijun

AU - Guo, Hui

AU - Kakizaki, Masako

AU - Cui, Yufei

AU - Ohmori-Matsuda, Kaori

AU - Guan, Lei

AU - Hozawa, Atsushi

AU - Kuriyama, Shinichi

AU - Tsuboya, Toru

AU - Ohrui, Takashi

AU - Furukawa, Katsutoshi

AU - Arai, Hiroyuki

AU - Tsuji, Ichiro

AU - Nagatomi, Ryoichi

PY - 2013/1/10

Y1 - 2013/1/10

N2 - Background: Enhanced oxidative stress or defective anti-oxidant defenses are related to the pathogenesis of depressive symptoms. Lycopene is the most powerful antioxidant amongst the carotenoids. The aim of this study was to investigate the relationship between different vegetables, including tomatoes/tomato products (a major source of lycopene), and depressive symptoms in a community-based elderly population. Methods: We analyzed a cross-sectional survey including 986 community-dwelling elderly Japanese individuals aged 70 years and older. Dietary intake was assessed using a valid self-administered diet-history questionnaire, and depressive symptoms were evaluated using the 30-item Geriatric Depression Scale with 2 cut-off points: 11 (mild and severe) and 14 (severe) or use of anti-depressive agents. Results: The prevalence of mild and severe and severe depressive symptoms was 34.9% and 20.2%, respectively. After adjustments for potentially confounding factors, the odds ratios of having mild and severe depressive symptoms by increasing levels of tomatoes/tomato products were 1.00, 0.54, and 0.48 (p for trend <0.01). Similar relationships were also observed in the case of severe depressive symptoms. In contrast, no relationship was observed between intake of other kinds of vegetables and depressive symptoms. Limitations: This is a cross-sectional study, and not for making a clinical diagnosis of depressive episodes. Conclusions: This study demonstrated that a tomato-rich diet is independently related to lower prevalence of depressive symptoms. These results suggest that a tomato-rich diet may have a beneficial effect on the prevention of depressive symptoms. Further studies are needed to confirm these findings.

AB - Background: Enhanced oxidative stress or defective anti-oxidant defenses are related to the pathogenesis of depressive symptoms. Lycopene is the most powerful antioxidant amongst the carotenoids. The aim of this study was to investigate the relationship between different vegetables, including tomatoes/tomato products (a major source of lycopene), and depressive symptoms in a community-based elderly population. Methods: We analyzed a cross-sectional survey including 986 community-dwelling elderly Japanese individuals aged 70 years and older. Dietary intake was assessed using a valid self-administered diet-history questionnaire, and depressive symptoms were evaluated using the 30-item Geriatric Depression Scale with 2 cut-off points: 11 (mild and severe) and 14 (severe) or use of anti-depressive agents. Results: The prevalence of mild and severe and severe depressive symptoms was 34.9% and 20.2%, respectively. After adjustments for potentially confounding factors, the odds ratios of having mild and severe depressive symptoms by increasing levels of tomatoes/tomato products were 1.00, 0.54, and 0.48 (p for trend <0.01). Similar relationships were also observed in the case of severe depressive symptoms. In contrast, no relationship was observed between intake of other kinds of vegetables and depressive symptoms. Limitations: This is a cross-sectional study, and not for making a clinical diagnosis of depressive episodes. Conclusions: This study demonstrated that a tomato-rich diet is independently related to lower prevalence of depressive symptoms. These results suggest that a tomato-rich diet may have a beneficial effect on the prevention of depressive symptoms. Further studies are needed to confirm these findings.

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