A variant mRNA species encoding a truncated form of Fas antigen in the rat liver

Kotohiko Kimura, Toru Wakatsuki, Mikio Yamamoto

Research output: Contribution to journalArticlepeer-review

41 Citations (Scopus)

Abstract

A variant form of the Fas antigen cDNA was isolated from the rat liver. The cDNA contains an insertion sequence of 25 nuecleotide residues and codes for a protein consisting of 65 amino acids representing a signal peptide and an N-terminal portion of the extracytoplasmic domain of Fas antigen. The expression of a variant mRNA species is less abundant in the liver compared with that of an ordinary mRNA species. The variant mRNA, though its function is unknown, is plausibly produced by an alternative splicing.

Original languageEnglish
Pages (from-to)666-674
Number of pages9
JournalBiochemical and Biophysical Research Communications
Volume198
Issue number2
DOIs
Publication statusPublished - 31-01-1994
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Biophysics
  • Biochemistry
  • Molecular Biology
  • Cell Biology

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