A variant form of the Fas antigen cDNA was isolated from the rat liver. The cDNA contains an insertion sequence of 25 nuecleotide residues and codes for a protein consisting of 65 amino acids representing a signal peptide and an N-terminal portion of the extracytoplasmic domain of Fas antigen. The expression of a variant mRNA species is less abundant in the liver compared with that of an ordinary mRNA species. The variant mRNA, though its function is unknown, is plausibly produced by an alternative splicing.
|Number of pages||9|
|Journal||Biochemical and Biophysical Research Communications|
|Publication status||Published - 31-01-1994|
All Science Journal Classification (ASJC) codes
- Molecular Biology
- Cell Biology