TY - JOUR
T1 - Abdominal apparent diffusion coefficient measurements
T2 - effect of diffusion-weighted image quality and usefulness of anisotropic images
AU - Yoshikawa, Takeshi
AU - Ohno, Yoshiharu
AU - Kawamitsu, Hideaki
AU - Ku, Yonson
AU - Seo, Yasushi
AU - Zamora, Carlos A.
AU - Aoyama, Nobukazu
AU - Sugimura, Kazuro
N1 - Funding Information:
This work was supported by the Smoking Research Foundation, Tokyo, Japan.
PY - 2008/12
Y1 - 2008/12
N2 - This study aimed to assess the effect of diffusion-weighted image (DWI) quality on abdominal apparent diffusion coefficient (ADC) measurements and the usefulness of anisotropic images. Twenty-six patients (10 men and 16 women; mean, 58.1 years) who underwent DW imaging and were diagnosed not to have any abdominal diseases were analyzed. Single-shot spin-echo echo-planar DW imaging was performed, and one isotropic and three orthogonal anisotropic images were created. ADCs were calculated for liver (four segments), spleen, pancreas (head, body, tail) and renal parenchyma. Image quality for each organ part was scored visually. We estimated the correlation between ADC and image quality and evaluated the feasibility of using anisotropic images. ADCs and image quality were affected by motion probing gradient directions in the liver and pancreas. A significant inverse correlation was found between ADC and image quality. The r values for isotropic images were -.46, -.48, -.70 and -.28 for the liver, spleen, pancreas and renal parenchyma, respectively. Anisotropic images had the best quality and lowest ADC in at least one organ part in 17 patients. DWIs with the best quality among isotropic and anisotropic images should be used in the liver and pancreas.
AB - This study aimed to assess the effect of diffusion-weighted image (DWI) quality on abdominal apparent diffusion coefficient (ADC) measurements and the usefulness of anisotropic images. Twenty-six patients (10 men and 16 women; mean, 58.1 years) who underwent DW imaging and were diagnosed not to have any abdominal diseases were analyzed. Single-shot spin-echo echo-planar DW imaging was performed, and one isotropic and three orthogonal anisotropic images were created. ADCs were calculated for liver (four segments), spleen, pancreas (head, body, tail) and renal parenchyma. Image quality for each organ part was scored visually. We estimated the correlation between ADC and image quality and evaluated the feasibility of using anisotropic images. ADCs and image quality were affected by motion probing gradient directions in the liver and pancreas. A significant inverse correlation was found between ADC and image quality. The r values for isotropic images were -.46, -.48, -.70 and -.28 for the liver, spleen, pancreas and renal parenchyma, respectively. Anisotropic images had the best quality and lowest ADC in at least one organ part in 17 patients. DWIs with the best quality among isotropic and anisotropic images should be used in the liver and pancreas.
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U2 - 10.1016/j.mri.2008.04.009
DO - 10.1016/j.mri.2008.04.009
M3 - Article
C2 - 18584985
AN - SCOPUS:55949112705
SN - 0730-725X
VL - 26
SP - 1415
EP - 1420
JO - Magnetic Resonance Imaging
JF - Magnetic Resonance Imaging
IS - 10
ER -