Abdominal radical trachelectomy as a fertility-sparing procedure in women with early-stage cervical cancer in a series of 61 women

Hiroshi Nishio, Takuma Fujii, Kaori Kameyama, Nobuyuki Susumu, Masaru Nakamura, Takashi Iwata, Daisuke Aoki

Research output: Contribution to journalArticle

88 Citations (Scopus)

Abstract

Objective: This retrospective study was conducted as a review of a series of women who had undergone abdominal radical trachelectomy and pelvic lymphadenectomy for early-stage cervical cancer. Methods: We performed a retrospective review of patients who had undergone an abdominal radical trachelectomy. Data regarding tumor size and histology, surgical complications, recurrences, pregnancies and live births were collected and were presented as a percentage of the total number of cases. Results: A total of 61 women were followed up for a median of 27 months (range: one month - 79 months). There were six recurrences (9.8%); none of the recurrences occurred in patients with a tumor diameter of < 20 mm except in one case with adenocarcinoma. Twenty-nine women attempted to conceive; four of these women were successful. All four of these women had live births: two had preterm deliveries, and the remaining two had full-term deliveries. The cumulative pregnancy rate among the women who attempted to conceive was 13.8% (4/29). Conclusion: Among selected women with early-stage cervical cancer, especially those with a tumor diameter of < 20 mm, abdominal radical trachelectomy and pelvic lymphadenectomy is a fertility-sparing treatment option, even though the cumulative conception rate was not particularly high compared with that for women who had undergone a vaginal radical trachelectomy.

Original languageEnglish
Pages (from-to)51-55
Number of pages5
JournalGynecologic Oncology
Volume115
Issue number1
DOIs
Publication statusPublished - 01-10-2009
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Oncology
  • Obstetrics and Gynaecology

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