Acid hydrolase activity of cultured bovine oligodendrocytes

Mikio Hirayama, Tatsuro Mutoh, Akira Tokuda

Research output: Contribution to journalArticlepeer-review


We measured the activity of several acid hydrolases of cultured oligodendrocytes prepared from adult bovine brain white matter to clarify the biochemical basis of bovine oligodendrocytes in vitro. Lysosomal enzyme activities were assayed by using 4-methylumbelliferyl glycosides as substrates. Lysosomal enzyme activities became higher at 8-11 days in vitro (DIV) than 4 DIV. The enrichment in acid hydrolase specific activities in oligodendrocytes may be associated with lysosomal origin of myelin-like membranes.

Original languageEnglish
Pages (from-to)121-124
Number of pages4
JournalNeurochemical Research
Issue number2
Publication statusPublished - 2001
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Cellular and Molecular Neuroscience


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