Acne management in Japan: Study of patient adherence

Yoshiki Miyachi, Nobukazu Hayashi, Fukumi Furukawa, Hirohiko Akamatsu, Kayoko Matsunaga, Shinichi Watanabe, Makoto Kawashima

Research output: Contribution to journalArticlepeer-review

32 Citations (Scopus)


Obtaining good adherence to acne therapy is a challenge for all dermatologists. We studied 428 acne patients in Japan to determine the likelihood of good adherence and factors associated with medication-taking. This study utilized a simple validated questionnaire to assess risk of poor adherence; information about patient and treatment characteristics was also collected. There was an overall rate of poor adherence in 76% of subjects. Adherence to topical medication was poor in 52% of those treated with a topical agent only (n = 123). Among those taking combination therapies (n = 275), adherence to the topical portion of therapy was poor in 49% of subjects. The likelihood of poor adherence to oral medication was higher, both when administered alone (n = 30, 93% poor adherence) and when given as part of a combination regimen (n = 275, 86%). Factors with an impact on adherence included satisfaction with treatment (p = 0.023) and the experience of side effects (p = 0.027). Patients who felt they had a good understanding of acne and its treatment were more likely to have good adherence. These data suggest that there is significant room for improvement in acne adherence in Japan, as in other areas of the world, and that improved education may enhance adherence.

Original languageEnglish
Pages (from-to)174-181
Number of pages8
Issue number2
Publication statusPublished - 11-2011

All Science Journal Classification (ASJC) codes

  • Dermatology


Dive into the research topics of 'Acne management in Japan: Study of patient adherence'. Together they form a unique fingerprint.

Cite this