Activity of eight fluoroquinolones against both methicillin-susceptible and -resistant Staphylococcus aureus isolated from skin infections

S. Nishijima; S. Namura; H. Akamatsu; S. Kawai; Y. Asada; S. Kawabata; M. Fujita

doi:10.1111/j.1346-8138.1995.tb03362.x

Activity of eight fluoroquinolones against both methicillin-susceptible and -resistant Staphylococcus aureus isolated from skin infections

S. Nishijima, S. Namura, H. Akamatsu, S. Kawai, Y. Asada, S. Kawabata, M. Fujita

Research output: Contribution to journal › Article › peer-review

4 Citations (Scopus)

Abstract

The in vitro susceptibility of Staphylococcus aureus to eight fluoroquinolones, norfloxacin, ofloxacin, enoxacin, ciprofloxacin, lomefloxacin, tosufloxacin, sparfloxacin, and nadifloxacin was established by agar dilution tests, 71 isolates of methicillin-susceptible (MSSA) and 74 isolates of -resistant S. aureus (MRSA) isolated from skin infections. Among all of the fluoroquinolones, nadifloxacin exhibited the lowest MIC for both MSSA and MRSA. In addition, there were no resistant S. aureus, neither MSSA and MRSA, to nadifloxacin. With the exception of nadifloxacin, the incidence of MRSA resistant to fluoroquinolones has gradually increased in recent years. Over half of the MRSA strains were resistant to norfloxacin, ofloxacin, enoxacin, ciprofloxacin, and lomefloxacin.

Original language	English
Pages (from-to)	153-155
Number of pages	3
Journal	Journal of Dermatology
Volume	22
Issue number	2
DOIs	https://doi.org/10.1111/j.1346-8138.1995.tb03362.x
Publication status	Published - 1995
Externally published	Yes

All Science Journal Classification (ASJC) codes

Dermatology

Access to Document

10.1111/j.1346-8138.1995.tb03362.x

Cite this

@article{6eccf807cfff4e0da58a58862b8f80b3,

title = "Activity of eight fluoroquinolones against both methicillin-susceptible and -resistant Staphylococcus aureus isolated from skin infections",

abstract = "The in vitro susceptibility of Staphylococcus aureus to eight fluoroquinolones, norfloxacin, ofloxacin, enoxacin, ciprofloxacin, lomefloxacin, tosufloxacin, sparfloxacin, and nadifloxacin was established by agar dilution tests, 71 isolates of methicillin-susceptible (MSSA) and 74 isolates of -resistant S. aureus (MRSA) isolated from skin infections. Among all of the fluoroquinolones, nadifloxacin exhibited the lowest MIC for both MSSA and MRSA. In addition, there were no resistant S. aureus, neither MSSA and MRSA, to nadifloxacin. With the exception of nadifloxacin, the incidence of MRSA resistant to fluoroquinolones has gradually increased in recent years. Over half of the MRSA strains were resistant to norfloxacin, ofloxacin, enoxacin, ciprofloxacin, and lomefloxacin.",

author = "S. Nishijima and S. Namura and H. Akamatsu and S. Kawai and Y. Asada and S. Kawabata and M. Fujita",

year = "1995",

doi = "10.1111/j.1346-8138.1995.tb03362.x",

language = "English",

volume = "22",

pages = "153--155",

journal = "Journal of Dermatology",

issn = "0385-2407",

publisher = "John Wiley and Sons Inc.",

number = "2",

}

TY - JOUR

T1 - Activity of eight fluoroquinolones against both methicillin-susceptible and -resistant Staphylococcus aureus isolated from skin infections

AU - Nishijima, S.

AU - Namura, S.

AU - Akamatsu, H.

AU - Kawai, S.

AU - Asada, Y.

AU - Kawabata, S.

AU - Fujita, M.

PY - 1995

Y1 - 1995

N2 - The in vitro susceptibility of Staphylococcus aureus to eight fluoroquinolones, norfloxacin, ofloxacin, enoxacin, ciprofloxacin, lomefloxacin, tosufloxacin, sparfloxacin, and nadifloxacin was established by agar dilution tests, 71 isolates of methicillin-susceptible (MSSA) and 74 isolates of -resistant S. aureus (MRSA) isolated from skin infections. Among all of the fluoroquinolones, nadifloxacin exhibited the lowest MIC for both MSSA and MRSA. In addition, there were no resistant S. aureus, neither MSSA and MRSA, to nadifloxacin. With the exception of nadifloxacin, the incidence of MRSA resistant to fluoroquinolones has gradually increased in recent years. Over half of the MRSA strains were resistant to norfloxacin, ofloxacin, enoxacin, ciprofloxacin, and lomefloxacin.

AB - The in vitro susceptibility of Staphylococcus aureus to eight fluoroquinolones, norfloxacin, ofloxacin, enoxacin, ciprofloxacin, lomefloxacin, tosufloxacin, sparfloxacin, and nadifloxacin was established by agar dilution tests, 71 isolates of methicillin-susceptible (MSSA) and 74 isolates of -resistant S. aureus (MRSA) isolated from skin infections. Among all of the fluoroquinolones, nadifloxacin exhibited the lowest MIC for both MSSA and MRSA. In addition, there were no resistant S. aureus, neither MSSA and MRSA, to nadifloxacin. With the exception of nadifloxacin, the incidence of MRSA resistant to fluoroquinolones has gradually increased in recent years. Over half of the MRSA strains were resistant to norfloxacin, ofloxacin, enoxacin, ciprofloxacin, and lomefloxacin.

UR - http://www.scopus.com/inward/record.url?scp=0028901480&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0028901480&partnerID=8YFLogxK

U2 - 10.1111/j.1346-8138.1995.tb03362.x

DO - 10.1111/j.1346-8138.1995.tb03362.x

M3 - Article

C2 - 7722093

AN - SCOPUS:0028901480

SN - 0385-2407

VL - 22

SP - 153

EP - 155

JO - Journal of Dermatology

JF - Journal of Dermatology

IS - 2

ER -

Activity of eight fluoroquinolones against both methicillin-susceptible and -resistant Staphylococcus aureus isolated from skin infections

Abstract

All Science Journal Classification (ASJC) codes

Access to Document

Other files and links

Fingerprint

Cite this