TY - JOUR
T1 - Activity of nadifloxacin against methicillin-resistant Staphylococcus aureus isolated from skin infections
T2 - Comparative study with seven other fluoroquinolones
AU - Nishijima, S.
AU - Nakagawa, M.
AU - Tsuboi, N.
AU - Akamatsu, H.
AU - Horio, T.
AU - Fujita, M.
AU - Kawabata, S.
N1 - Copyright:
Copyright 2017 Elsevier B.V., All rights reserved.
PY - 1996
Y1 - 1996
N2 - The in vitro susceptibility of methicillin-resistant Staphylococcus aureus (MRSA) to nadifloxacin and seven other fluoroquinolones (norfloxacin, ofloxacin, enoxacin, ciprofloxacin, lomefloxacin, tosufloxacin and sparfloxacin) was evaluated. The MRSA isolates were isolated from 114 skin infections between 1991 and 1994. Nadifloxacin exhibited the lowest minimum inhibitory concentration and there were no MRSA isolates resistant to nadifloxacin, while there were some resistant to all of the other seven fluoroquinolones. The minimum concentrations of these drugs needed to cause 50% inhibition of the isolates increased dramatically from 1991 to 1992, but has hardly changed since 1992.
AB - The in vitro susceptibility of methicillin-resistant Staphylococcus aureus (MRSA) to nadifloxacin and seven other fluoroquinolones (norfloxacin, ofloxacin, enoxacin, ciprofloxacin, lomefloxacin, tosufloxacin and sparfloxacin) was evaluated. The MRSA isolates were isolated from 114 skin infections between 1991 and 1994. Nadifloxacin exhibited the lowest minimum inhibitory concentration and there were no MRSA isolates resistant to nadifloxacin, while there were some resistant to all of the other seven fluoroquinolones. The minimum concentrations of these drugs needed to cause 50% inhibition of the isolates increased dramatically from 1991 to 1992, but has hardly changed since 1992.
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U2 - 10.1177/030006059602400102
DO - 10.1177/030006059602400102
M3 - Article
C2 - 8674789
AN - SCOPUS:0030039017
SN - 0300-0605
VL - 24
SP - 12
EP - 16
JO - Journal of International Medical Research
JF - Journal of International Medical Research
IS - 1
ER -