Acute autonomic, sensory and motor neuropathy

Successful treatment with IVIg

Akihiro Ueda, Kunihiko Asakura, Takateru Mihara, Hideo Hara, Madoka Ueda, Tadayuki Miyashita, Tatsuro Mutoh

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

Acute autonomic, sensory and motor neuropathy (AASMN) is a rare peripheral nerve disorder characterized by prominent dysautonomia with somatic sensory and motor impairment. Dysautonomia in AASMN is intractable even with corticosteroid therapy or plasmapheresis. Here we report a case of AASMN with severe orthostatic hypotension. Although the effectiveness of corticosteroid was insufficient, high dose intravenous immunoglobulin therapy (IVIg) was effective for not only sensorimotor symptoms but also autonomic symptoms. This is the first case of AASMN showing favorable responses to IVIg treatment, suggesting that IVIg should be considered when corticosteroid therapy or plasmapheresis is ineffective or insufficient.

Original languageEnglish
Pages (from-to)843-846
Number of pages4
JournalInternal Medicine
Volume48
Issue number10
DOIs
Publication statusPublished - 13-07-2009

Fingerprint

Passive Immunization
Intravenous Immunoglobulins
Primary Dysautonomias
Adrenal Cortex Hormones
Plasmapheresis
Orthostatic Hypotension
Peripheral Nerves
Therapeutics

All Science Journal Classification (ASJC) codes

  • Internal Medicine

Cite this

Ueda, A., Asakura, K., Mihara, T., Hara, H., Ueda, M., Miyashita, T., & Mutoh, T. (2009). Acute autonomic, sensory and motor neuropathy: Successful treatment with IVIg. Internal Medicine, 48(10), 843-846. https://doi.org/10.2169/internalmedicine.48.1848
Ueda, Akihiro ; Asakura, Kunihiko ; Mihara, Takateru ; Hara, Hideo ; Ueda, Madoka ; Miyashita, Tadayuki ; Mutoh, Tatsuro. / Acute autonomic, sensory and motor neuropathy : Successful treatment with IVIg. In: Internal Medicine. 2009 ; Vol. 48, No. 10. pp. 843-846.
@article{9eab795e86cf4d17a01741c36237c998,
title = "Acute autonomic, sensory and motor neuropathy: Successful treatment with IVIg",
abstract = "Acute autonomic, sensory and motor neuropathy (AASMN) is a rare peripheral nerve disorder characterized by prominent dysautonomia with somatic sensory and motor impairment. Dysautonomia in AASMN is intractable even with corticosteroid therapy or plasmapheresis. Here we report a case of AASMN with severe orthostatic hypotension. Although the effectiveness of corticosteroid was insufficient, high dose intravenous immunoglobulin therapy (IVIg) was effective for not only sensorimotor symptoms but also autonomic symptoms. This is the first case of AASMN showing favorable responses to IVIg treatment, suggesting that IVIg should be considered when corticosteroid therapy or plasmapheresis is ineffective or insufficient.",
author = "Akihiro Ueda and Kunihiko Asakura and Takateru Mihara and Hideo Hara and Madoka Ueda and Tadayuki Miyashita and Tatsuro Mutoh",
year = "2009",
month = "7",
day = "13",
doi = "10.2169/internalmedicine.48.1848",
language = "English",
volume = "48",
pages = "843--846",
journal = "Internal Medicine",
issn = "0918-2918",
publisher = "Japanese Society of Internal Medicine",
number = "10",

}

Ueda, A, Asakura, K, Mihara, T, Hara, H, Ueda, M, Miyashita, T & Mutoh, T 2009, 'Acute autonomic, sensory and motor neuropathy: Successful treatment with IVIg', Internal Medicine, vol. 48, no. 10, pp. 843-846. https://doi.org/10.2169/internalmedicine.48.1848

Acute autonomic, sensory and motor neuropathy : Successful treatment with IVIg. / Ueda, Akihiro; Asakura, Kunihiko; Mihara, Takateru; Hara, Hideo; Ueda, Madoka; Miyashita, Tadayuki; Mutoh, Tatsuro.

In: Internal Medicine, Vol. 48, No. 10, 13.07.2009, p. 843-846.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Acute autonomic, sensory and motor neuropathy

T2 - Successful treatment with IVIg

AU - Ueda, Akihiro

AU - Asakura, Kunihiko

AU - Mihara, Takateru

AU - Hara, Hideo

AU - Ueda, Madoka

AU - Miyashita, Tadayuki

AU - Mutoh, Tatsuro

PY - 2009/7/13

Y1 - 2009/7/13

N2 - Acute autonomic, sensory and motor neuropathy (AASMN) is a rare peripheral nerve disorder characterized by prominent dysautonomia with somatic sensory and motor impairment. Dysautonomia in AASMN is intractable even with corticosteroid therapy or plasmapheresis. Here we report a case of AASMN with severe orthostatic hypotension. Although the effectiveness of corticosteroid was insufficient, high dose intravenous immunoglobulin therapy (IVIg) was effective for not only sensorimotor symptoms but also autonomic symptoms. This is the first case of AASMN showing favorable responses to IVIg treatment, suggesting that IVIg should be considered when corticosteroid therapy or plasmapheresis is ineffective or insufficient.

AB - Acute autonomic, sensory and motor neuropathy (AASMN) is a rare peripheral nerve disorder characterized by prominent dysautonomia with somatic sensory and motor impairment. Dysautonomia in AASMN is intractable even with corticosteroid therapy or plasmapheresis. Here we report a case of AASMN with severe orthostatic hypotension. Although the effectiveness of corticosteroid was insufficient, high dose intravenous immunoglobulin therapy (IVIg) was effective for not only sensorimotor symptoms but also autonomic symptoms. This is the first case of AASMN showing favorable responses to IVIg treatment, suggesting that IVIg should be considered when corticosteroid therapy or plasmapheresis is ineffective or insufficient.

UR - http://www.scopus.com/inward/record.url?scp=67649964677&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=67649964677&partnerID=8YFLogxK

U2 - 10.2169/internalmedicine.48.1848

DO - 10.2169/internalmedicine.48.1848

M3 - Article

VL - 48

SP - 843

EP - 846

JO - Internal Medicine

JF - Internal Medicine

SN - 0918-2918

IS - 10

ER -