Acute retinal necrosis after corticosteroid pulse therapy for unilateral vogt-koyanagi-harada disease

Reiko Yokoi, Tetsu Asami, Shu Kachi, Yasuki Ito, Makoto Nakamura, Hiroko Terasaki

Research output: Contribution to journalArticlepeer-review

2 Citations (Scopus)

Abstract

Purpose: To report on a patient with unilateral Vogt-Koyanagi-Harada (VKH) disease who developed varicella zoster-associated acute retinal necrosis after corticosteroid pulse therapy for the VKH disease. Methods: Observational case report. Results: A 36-year-old Japanese man was diagnosed with incomplete VKH disease despite having only unilateral changes. After corticosteroid pulse therapy, the same eye developed acute retinal necrosis. Polymerase chain reaction of an aqueous humor specimen showed DNA of the varicella zoster virus. Seven days after intravenous acyclovir, the retinitis disappeared. Conclusion: We encountered a rare case of unilateral VKH disease that developed acute retinal necrosis during corticosteroid pulse therapy. Acute retinal necrosis can develop during corticosteroid pulse therapy for VKH disease.

Original languageEnglish
Pages (from-to)51-54
Number of pages4
JournalRetinal Cases and Brief Reports
Volume4
Issue number1
DOIs
Publication statusPublished - 12-2010
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Ophthalmology

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