TY - JOUR
T1 - Acute retinal necrosis after corticosteroid pulse therapy for unilateral vogt-koyanagi-harada disease
AU - Yokoi, Reiko
AU - Asami, Tetsu
AU - Kachi, Shu
AU - Ito, Yasuki
AU - Nakamura, Makoto
AU - Terasaki, Hiroko
PY - 2010/12
Y1 - 2010/12
N2 - Purpose: To report on a patient with unilateral Vogt-Koyanagi-Harada (VKH) disease who developed varicella zoster-associated acute retinal necrosis after corticosteroid pulse therapy for the VKH disease. Methods: Observational case report. Results: A 36-year-old Japanese man was diagnosed with incomplete VKH disease despite having only unilateral changes. After corticosteroid pulse therapy, the same eye developed acute retinal necrosis. Polymerase chain reaction of an aqueous humor specimen showed DNA of the varicella zoster virus. Seven days after intravenous acyclovir, the retinitis disappeared. Conclusion: We encountered a rare case of unilateral VKH disease that developed acute retinal necrosis during corticosteroid pulse therapy. Acute retinal necrosis can develop during corticosteroid pulse therapy for VKH disease.
AB - Purpose: To report on a patient with unilateral Vogt-Koyanagi-Harada (VKH) disease who developed varicella zoster-associated acute retinal necrosis after corticosteroid pulse therapy for the VKH disease. Methods: Observational case report. Results: A 36-year-old Japanese man was diagnosed with incomplete VKH disease despite having only unilateral changes. After corticosteroid pulse therapy, the same eye developed acute retinal necrosis. Polymerase chain reaction of an aqueous humor specimen showed DNA of the varicella zoster virus. Seven days after intravenous acyclovir, the retinitis disappeared. Conclusion: We encountered a rare case of unilateral VKH disease that developed acute retinal necrosis during corticosteroid pulse therapy. Acute retinal necrosis can develop during corticosteroid pulse therapy for VKH disease.
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U2 - 10.1097/ICB.0b013e318196b221
DO - 10.1097/ICB.0b013e318196b221
M3 - Article
AN - SCOPUS:80052244798
SN - 1935-1089
VL - 4
SP - 51
EP - 54
JO - Retinal Cases and Brief Reports
JF - Retinal Cases and Brief Reports
IS - 1
ER -