Acute retinal necrosis after corticosteroid pulse therapy for unilateral vogt-koyanagi-harada disease

Reiko Yokoi; Tetsu Asami; Shu Kachi; Yasuki Ito; Makoto Nakamura; Hiroko Terasaki

doi:10.1097/ICB.0b013e318196b221

Acute retinal necrosis after corticosteroid pulse therapy for unilateral vogt-koyanagi-harada disease

Reiko Yokoi
, Tetsu Asami
, Shu Kachi
, Yasuki Ito
, Makoto Nakamura
, Hiroko Terasaki

Research output: Contribution to journal › Article › peer-review

4 Citations (Scopus)

Abstract

Purpose: To report on a patient with unilateral Vogt-Koyanagi-Harada (VKH) disease who developed varicella zoster-associated acute retinal necrosis after corticosteroid pulse therapy for the VKH disease. Methods: Observational case report. Results: A 36-year-old Japanese man was diagnosed with incomplete VKH disease despite having only unilateral changes. After corticosteroid pulse therapy, the same eye developed acute retinal necrosis. Polymerase chain reaction of an aqueous humor specimen showed DNA of the varicella zoster virus. Seven days after intravenous acyclovir, the retinitis disappeared. Conclusion: We encountered a rare case of unilateral VKH disease that developed acute retinal necrosis during corticosteroid pulse therapy. Acute retinal necrosis can develop during corticosteroid pulse therapy for VKH disease.

Original language	English
Pages (from-to)	51-54
Number of pages	4
Journal	Retinal Cases and Brief Reports
Volume	4
Issue number	1
DOIs	https://doi.org/10.1097/ICB.0b013e318196b221
Publication status	Published - 12-2010
Externally published	Yes

All Science Journal Classification (ASJC) codes

Ophthalmology

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10.1097/ICB.0b013e318196b221

Cite this

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title = "Acute retinal necrosis after corticosteroid pulse therapy for unilateral vogt-koyanagi-harada disease",

abstract = "Purpose: To report on a patient with unilateral Vogt-Koyanagi-Harada (VKH) disease who developed varicella zoster-associated acute retinal necrosis after corticosteroid pulse therapy for the VKH disease. Methods: Observational case report. Results: A 36-year-old Japanese man was diagnosed with incomplete VKH disease despite having only unilateral changes. After corticosteroid pulse therapy, the same eye developed acute retinal necrosis. Polymerase chain reaction of an aqueous humor specimen showed DNA of the varicella zoster virus. Seven days after intravenous acyclovir, the retinitis disappeared. Conclusion: We encountered a rare case of unilateral VKH disease that developed acute retinal necrosis during corticosteroid pulse therapy. Acute retinal necrosis can develop during corticosteroid pulse therapy for VKH disease.",

author = "Reiko Yokoi and Tetsu Asami and Shu Kachi and Yasuki Ito and Makoto Nakamura and Hiroko Terasaki",

year = "2010",

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doi = "10.1097/ICB.0b013e318196b221",

language = "English",

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T1 - Acute retinal necrosis after corticosteroid pulse therapy for unilateral vogt-koyanagi-harada disease

AU - Yokoi, Reiko

AU - Asami, Tetsu

AU - Kachi, Shu

AU - Ito, Yasuki

AU - Nakamura, Makoto

AU - Terasaki, Hiroko

PY - 2010/12

Y1 - 2010/12

N2 - Purpose: To report on a patient with unilateral Vogt-Koyanagi-Harada (VKH) disease who developed varicella zoster-associated acute retinal necrosis after corticosteroid pulse therapy for the VKH disease. Methods: Observational case report. Results: A 36-year-old Japanese man was diagnosed with incomplete VKH disease despite having only unilateral changes. After corticosteroid pulse therapy, the same eye developed acute retinal necrosis. Polymerase chain reaction of an aqueous humor specimen showed DNA of the varicella zoster virus. Seven days after intravenous acyclovir, the retinitis disappeared. Conclusion: We encountered a rare case of unilateral VKH disease that developed acute retinal necrosis during corticosteroid pulse therapy. Acute retinal necrosis can develop during corticosteroid pulse therapy for VKH disease.

AB - Purpose: To report on a patient with unilateral Vogt-Koyanagi-Harada (VKH) disease who developed varicella zoster-associated acute retinal necrosis after corticosteroid pulse therapy for the VKH disease. Methods: Observational case report. Results: A 36-year-old Japanese man was diagnosed with incomplete VKH disease despite having only unilateral changes. After corticosteroid pulse therapy, the same eye developed acute retinal necrosis. Polymerase chain reaction of an aqueous humor specimen showed DNA of the varicella zoster virus. Seven days after intravenous acyclovir, the retinitis disappeared. Conclusion: We encountered a rare case of unilateral VKH disease that developed acute retinal necrosis during corticosteroid pulse therapy. Acute retinal necrosis can develop during corticosteroid pulse therapy for VKH disease.

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DO - 10.1097/ICB.0b013e318196b221

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ER -

Acute retinal necrosis after corticosteroid pulse therapy for unilateral vogt-koyanagi-harada disease

Abstract

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