Age-Appropriateness of Porcine Models Used for Cell Transplantation

Shugo Tohyama; Eiji Kobayashi

doi:10.1177/0963689718817477

Age-Appropriateness of Porcine Models Used for Cell Transplantation

Shugo Tohyama
, Eiji Kobayashi

Research output: Contribution to journal › Comment/debate › peer-review

36 Citations (Scopus)

Abstract

Pigs have traditionally been used for preclinical experiments, and body size-matching is important for cell therapy in animal models used for preclinical trials. It has been shown that the efficacy of the transplanted cells is dependent on the response of the host heart and the age of experimental pigs.

Original language	English
Pages (from-to)	224-228
Number of pages	5
Journal	Cell Transplantation
Volume	28
Issue number	2
DOIs	https://doi.org/10.1177/0963689718817477
Publication status	Published - 01-02-2019
Externally published	Yes

All Science Journal Classification (ASJC) codes

Biomedical Engineering
Cell Biology
Transplantation

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Cite this

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title = "Age-Appropriateness of Porcine Models Used for Cell Transplantation",

abstract = "Pigs have traditionally been used for preclinical experiments, and body size-matching is important for cell therapy in animal models used for preclinical trials. It has been shown that the efficacy of the transplanted cells is dependent on the response of the host heart and the age of experimental pigs.",

keywords = "Stem cell, age, cell transplantation, myocardial infarction, pig",

author = "Shugo Tohyama and Eiji Kobayashi",

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AU - Tohyama, Shugo

AU - Kobayashi, Eiji

N1 - Publisher Copyright: © The Author(s) 2018.

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Y1 - 2019/2/1

N2 - Pigs have traditionally been used for preclinical experiments, and body size-matching is important for cell therapy in animal models used for preclinical trials. It has been shown that the efficacy of the transplanted cells is dependent on the response of the host heart and the age of experimental pigs.

AB - Pigs have traditionally been used for preclinical experiments, and body size-matching is important for cell therapy in animal models used for preclinical trials. It has been shown that the efficacy of the transplanted cells is dependent on the response of the host heart and the age of experimental pigs.

KW - Stem cell

KW - age

KW - cell transplantation

KW - myocardial infarction

KW - pig

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Age-Appropriateness of Porcine Models Used for Cell Transplantation

Abstract

All Science Journal Classification (ASJC) codes

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