ALK Gene Translocation in Inflammatory Myofibroblastic Tumor of the Urinary Bladder: A Case Report

Kimiaki Takagi; Manabu Takai; Koji Kameyama; Kengo Horie; Mina Kikuchi; Taku Kato; Kosuke Mizutani; Kensaku Seike; Tomohiro Tsuchiya; Mitsuru Yasuda; Shigeaki Yokoi; Natsuko Suzui; Masahiro Nakano; Takashi Deguchi

doi:10.1016/j.eucr.2015.06.003

ALK Gene Translocation in Inflammatory Myofibroblastic Tumor of the Urinary Bladder: A Case Report

Kimiaki Takagi, Manabu Takai, Koji Kameyama, Kengo Horie, Mina Kikuchi, Taku Kato, Kosuke Mizutani, Kensaku Seike, Tomohiro Tsuchiya, Mitsuru Yasuda, Shigeaki Yokoi, Natsuko Suzui, Masahiro Nakano, Takashi Deguchi

Research output: Contribution to journal › Article › peer-review

6 Citations (Scopus)

Abstract

A 26-year-old woman with gross hematuria was seen in a previous hospital. Magnetic resonance imaging (MRI) showed a tumor at the dome of the urinary bladder with invasion outside of the bladder wall. The patient underwent transurethral resection of the bladder tumor (TUR-BT). From the result of the pathological examination, the tumor was suggested to be carcinosarcoma of the bladder. The patient was then referred to our hospital for treatment. We performed radical cystectomy and ileal conduit diversion. Pathological examination of the excised specimen revealed an inflammatory myofibroblastic tumor as the basis for immunostaining of anaplastic lymphoma kinase (ALK).

Original language	English
Pages (from-to)	138-140
Number of pages	3
Journal	Urology Case Reports
Volume	3
Issue number	5
DOIs	https://doi.org/10.1016/j.eucr.2015.06.003
Publication status	Published - 01-09-2015
Externally published	Yes

All Science Journal Classification (ASJC) codes

Urology

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10.1016/j.eucr.2015.06.003

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title = "ALK Gene Translocation in Inflammatory Myofibroblastic Tumor of the Urinary Bladder: A Case Report",

abstract = "A 26-year-old woman with gross hematuria was seen in a previous hospital. Magnetic resonance imaging (MRI) showed a tumor at the dome of the urinary bladder with invasion outside of the bladder wall. The patient underwent transurethral resection of the bladder tumor (TUR-BT). From the result of the pathological examination, the tumor was suggested to be carcinosarcoma of the bladder. The patient was then referred to our hospital for treatment. We performed radical cystectomy and ileal conduit diversion. Pathological examination of the excised specimen revealed an inflammatory myofibroblastic tumor as the basis for immunostaining of anaplastic lymphoma kinase (ALK).",

keywords = "ALK, Bladder tumor, FISH, Inflammatory myofibroblastic tumor",

author = "Kimiaki Takagi and Manabu Takai and Koji Kameyama and Kengo Horie and Mina Kikuchi and Taku Kato and Kosuke Mizutani and Kensaku Seike and Tomohiro Tsuchiya and Mitsuru Yasuda and Shigeaki Yokoi and Natsuko Suzui and Masahiro Nakano and Takashi Deguchi",

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year = "2015",

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doi = "10.1016/j.eucr.2015.06.003",

language = "English",

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TY - JOUR

T1 - ALK Gene Translocation in Inflammatory Myofibroblastic Tumor of the Urinary Bladder

T2 - A Case Report

AU - Takagi, Kimiaki

AU - Takai, Manabu

AU - Kameyama, Koji

AU - Horie, Kengo

AU - Kikuchi, Mina

AU - Kato, Taku

AU - Mizutani, Kosuke

AU - Seike, Kensaku

AU - Tsuchiya, Tomohiro

AU - Yasuda, Mitsuru

AU - Yokoi, Shigeaki

AU - Suzui, Natsuko

AU - Nakano, Masahiro

AU - Deguchi, Takashi

PY - 2015/9/1

Y1 - 2015/9/1

N2 - A 26-year-old woman with gross hematuria was seen in a previous hospital. Magnetic resonance imaging (MRI) showed a tumor at the dome of the urinary bladder with invasion outside of the bladder wall. The patient underwent transurethral resection of the bladder tumor (TUR-BT). From the result of the pathological examination, the tumor was suggested to be carcinosarcoma of the bladder. The patient was then referred to our hospital for treatment. We performed radical cystectomy and ileal conduit diversion. Pathological examination of the excised specimen revealed an inflammatory myofibroblastic tumor as the basis for immunostaining of anaplastic lymphoma kinase (ALK).

AB - A 26-year-old woman with gross hematuria was seen in a previous hospital. Magnetic resonance imaging (MRI) showed a tumor at the dome of the urinary bladder with invasion outside of the bladder wall. The patient underwent transurethral resection of the bladder tumor (TUR-BT). From the result of the pathological examination, the tumor was suggested to be carcinosarcoma of the bladder. The patient was then referred to our hospital for treatment. We performed radical cystectomy and ileal conduit diversion. Pathological examination of the excised specimen revealed an inflammatory myofibroblastic tumor as the basis for immunostaining of anaplastic lymphoma kinase (ALK).

KW - ALK

KW - Bladder tumor

KW - FISH

KW - Inflammatory myofibroblastic tumor

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DO - 10.1016/j.eucr.2015.06.003

M3 - Article

AN - SCOPUS:84940450802

SN - 2214-4420

VL - 3

SP - 138

EP - 140

JO - Urology Case Reports

JF - Urology Case Reports

IS - 5

ER -

ALK Gene Translocation in Inflammatory Myofibroblastic Tumor of the Urinary Bladder: A Case Report

Abstract

All Science Journal Classification (ASJC) codes

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