Aloe arborescens extract inhibits TPA-induced ear oedema, putrescine increase and tumour promotion in mouse skin

Kan Shimpo; Chikako Ida; Takeshi Chihara; Hidehiko Beppu; Takaaki Kaneko; Hiroshi Kuzuya

doi:10.1002/ptr.938

Aloe arborescens extract inhibits TPA-induced ear oedema, putrescine increase and tumour promotion in mouse skin

Kan Shimpo, Chikako Ida, Takeshi Chihara, Hidehiko Beppu, Takaaki Kaneko, Hiroshi Kuzuya

Research output: Contribution to journal › Article › peer-review

15 Citations (Scopus)

Abstract

The ethyl acetate extract of the acetone-soluble Aloe arborescens fraction was found to inhibit 12-O-tetradecanoylphorbol-13-acetate (TPA)-induced ear oedema, putrescine increase and tumour promotion in mouse skin. Chromatographic analyses of this extract revealed that phenolic compounds such as aloenin, barbaloin and isobarbaloin could be useful as cancer chemopreventive agents against tumour promotion.

Original language	English
Pages (from-to)	491-493
Number of pages	3
Journal	Phytotherapy Research
Volume	16
Issue number	5
DOIs	https://doi.org/10.1002/ptr.938
Publication status	Published - 08-2002
Externally published	Yes

All Science Journal Classification (ASJC) codes

Pharmacology

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10.1002/ptr.938

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title = "Aloe arborescens extract inhibits TPA-induced ear oedema, putrescine increase and tumour promotion in mouse skin",

abstract = "The ethyl acetate extract of the acetone-soluble Aloe arborescens fraction was found to inhibit 12-O-tetradecanoylphorbol-13-acetate (TPA)-induced ear oedema, putrescine increase and tumour promotion in mouse skin. Chromatographic analyses of this extract revealed that phenolic compounds such as aloenin, barbaloin and isobarbaloin could be useful as cancer chemopreventive agents against tumour promotion.",

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AU - Shimpo, Kan

AU - Ida, Chikako

AU - Chihara, Takeshi

AU - Beppu, Hidehiko

AU - Kaneko, Takaaki

AU - Kuzuya, Hiroshi

PY - 2002/8

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AB - The ethyl acetate extract of the acetone-soluble Aloe arborescens fraction was found to inhibit 12-O-tetradecanoylphorbol-13-acetate (TPA)-induced ear oedema, putrescine increase and tumour promotion in mouse skin. Chromatographic analyses of this extract revealed that phenolic compounds such as aloenin, barbaloin and isobarbaloin could be useful as cancer chemopreventive agents against tumour promotion.

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Aloe arborescens extract inhibits TPA-induced ear oedema, putrescine increase and tumour promotion in mouse skin

Abstract

All Science Journal Classification (ASJC) codes

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