Aloe arborescens extract inhibits TPA-induced ear oedema, putrescine increase and tumour promotion in mouse skin

Kan Shimpo, Chikako Ida, Takeshi Chihara, Hidehiko Beppu, Takaaki Kaneko, Hiroshi Kuzuya

Research output: Contribution to journalArticle

16 Citations (Scopus)

Abstract

The ethyl acetate extract of the acetone-soluble Aloe arborescens fraction was found to inhibit 12-O-tetradecanoylphorbol-13-acetate (TPA)-induced ear oedema, putrescine increase and tumour promotion in mouse skin. Chromatographic analyses of this extract revealed that phenolic compounds such as aloenin, barbaloin and isobarbaloin could be useful as cancer chemopreventive agents against tumour promotion.

Original languageEnglish
Pages (from-to)491-493
Number of pages3
JournalPhytotherapy Research
Volume16
Issue number5
DOIs
Publication statusPublished - 01-08-2002

Fingerprint

Aloe
Putrescine
Tetradecanoylphorbol Acetate
Ear
Tumors
Edema
Skin
Acetates
Acetone
Neoplasms
Chromatography
barbaloin
aloenin
ethyl acetate

All Science Journal Classification (ASJC) codes

  • Pharmacology

Cite this

Shimpo, Kan ; Ida, Chikako ; Chihara, Takeshi ; Beppu, Hidehiko ; Kaneko, Takaaki ; Kuzuya, Hiroshi. / Aloe arborescens extract inhibits TPA-induced ear oedema, putrescine increase and tumour promotion in mouse skin. In: Phytotherapy Research. 2002 ; Vol. 16, No. 5. pp. 491-493.
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Aloe arborescens extract inhibits TPA-induced ear oedema, putrescine increase and tumour promotion in mouse skin. / Shimpo, Kan; Ida, Chikako; Chihara, Takeshi; Beppu, Hidehiko; Kaneko, Takaaki; Kuzuya, Hiroshi.

In: Phytotherapy Research, Vol. 16, No. 5, 01.08.2002, p. 491-493.

Research output: Contribution to journalArticle

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