Amines and pteridines

K. Shimpo; Takeshi Chihara; M. Hibiya; S. Ito; T. Nagatsu

Amines and pteridines

K. Shimpo
, Takeshi Chihara
, M. Hibiya
, S. Ito
, T. Nagatsu

Research output: Contribution to journal › Review article › peer-review

Abstract

Polyamines (putrescine, spermidine and spermine) play important roles in cell proliferation and differentiation, and have been established as tumors markers. We and other workers have confirmed that N1-acetylspermidine in tumor tissues, spermidine and spermine in erythrocytes, and N1,N12-diacetylspermine in urine might be the most sensitive indicators for various forms of tumors. Neopterin is a marker of cell-mediated immunostimulation, and may be a helpful marker in monitoring cancer patients. HPLC and immunological assays of neopterin, biopterin, and N2-(3-aminopropyl)biopterin(oncopterin) in urine might be useful in the clinical study of pteridines, as cancer markers. Serum 5-S-cysteinyldopa level is a useful and specific biochemical marker for malignant melanoma.

Original language	English
Pages (from-to)	1515-1520
Number of pages	6
Journal	Nippon rinsho. Japanese journal of clinical medicine
Volume	54
Issue number	6
Publication status	Published - 06-1996
Externally published	Yes

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

All Science Journal Classification (ASJC) codes

General Medicine

Cite this

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title = "Amines and pteridines",

abstract = "Polyamines (putrescine, spermidine and spermine) play important roles in cell proliferation and differentiation, and have been established as tumors markers. We and other workers have confirmed that N1-acetylspermidine in tumor tissues, spermidine and spermine in erythrocytes, and N1,N12-diacetylspermine in urine might be the most sensitive indicators for various forms of tumors. Neopterin is a marker of cell-mediated immunostimulation, and may be a helpful marker in monitoring cancer patients. HPLC and immunological assays of neopterin, biopterin, and N2-(3-aminopropyl)biopterin(oncopterin) in urine might be useful in the clinical study of pteridines, as cancer markers. Serum 5-S-cysteinyldopa level is a useful and specific biochemical marker for malignant melanoma.",

author = "K. Shimpo and Takeshi Chihara and M. Hibiya and S. Ito and T. Nagatsu",

note = "Copyright: This record is sourced from MEDLINE{\textregistered}/PubMed{\textregistered}, a database of the U.S. National Library of Medicine",

year = "1996",

month = jun,

language = "English",

volume = "54",

pages = "1515--1520",

journal = "Nippon rinsho. Japanese journal of clinical medicine",

issn = "0047-1852",

publisher = "Nipponrinsho Co., Inc.",

number = "6",

}

TY - JOUR

T1 - Amines and pteridines

AU - Shimpo, K.

AU - Chihara, Takeshi

AU - Hibiya, M.

AU - Ito, S.

AU - Nagatsu, T.

N1 - Copyright: This record is sourced from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

PY - 1996/6

Y1 - 1996/6

N2 - Polyamines (putrescine, spermidine and spermine) play important roles in cell proliferation and differentiation, and have been established as tumors markers. We and other workers have confirmed that N1-acetylspermidine in tumor tissues, spermidine and spermine in erythrocytes, and N1,N12-diacetylspermine in urine might be the most sensitive indicators for various forms of tumors. Neopterin is a marker of cell-mediated immunostimulation, and may be a helpful marker in monitoring cancer patients. HPLC and immunological assays of neopterin, biopterin, and N2-(3-aminopropyl)biopterin(oncopterin) in urine might be useful in the clinical study of pteridines, as cancer markers. Serum 5-S-cysteinyldopa level is a useful and specific biochemical marker for malignant melanoma.

AB - Polyamines (putrescine, spermidine and spermine) play important roles in cell proliferation and differentiation, and have been established as tumors markers. We and other workers have confirmed that N1-acetylspermidine in tumor tissues, spermidine and spermine in erythrocytes, and N1,N12-diacetylspermine in urine might be the most sensitive indicators for various forms of tumors. Neopterin is a marker of cell-mediated immunostimulation, and may be a helpful marker in monitoring cancer patients. HPLC and immunological assays of neopterin, biopterin, and N2-(3-aminopropyl)biopterin(oncopterin) in urine might be useful in the clinical study of pteridines, as cancer markers. Serum 5-S-cysteinyldopa level is a useful and specific biochemical marker for malignant melanoma.

UR - https://www.scopus.com/pages/publications/0030164072

UR - https://www.scopus.com/pages/publications/0030164072#tab=citedBy

M3 - Review article

C2 - 8691603

AN - SCOPUS:0030164072

SN - 0047-1852

VL - 54

SP - 1515

EP - 1520

JO - Nippon rinsho. Japanese journal of clinical medicine

JF - Nippon rinsho. Japanese journal of clinical medicine

IS - 6

ER -

Amines and pteridines

Abstract

UN SDGs

All Science Journal Classification (ASJC) codes

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