An adult case of generalized convulsions caused by the ingestion of ginkgo biloba seeds with alcohol

Fumika Azuma, Kazuya Nokura, Tetsuharu Kako, Daisuke Kobayashi, Teruki Yoshimura, Keiji Wada

Research output: Contribution to journalArticle

Abstract

A 64-year-old woman developed symptoms of vomiting and tonic-clonic convulsions 9.5 h after eating 50 roasted Ginkgo biloba seeds with 100 g of alcohol. The intravenous administration of pyridoxal phosphate effectively improved the symptoms. Blood samples were collected and stored over 35 h. The assessment of 4'- O-methylpyridoxine and vitamin B6 vitamers indicated high levels of both, but the pyridoxal phosphate levels were low during the acute stage. These results suggest that 4'-O-methylpyridoxine inhibits the transformation of vitamin B6 analogues to the active form, pyridoxal phosphate. In our case, alcohol may have extended the period until ginkgo intoxication appeared.

Original languageEnglish
Pages (from-to)1555-1558
Number of pages4
JournalInternal Medicine
Volume59
Issue number12
DOIs
Publication statusPublished - 15-06-2020

All Science Journal Classification (ASJC) codes

  • Internal Medicine

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