An autopsy case report of fulminant myocarditis: Following mRNA COVID-19 vaccination

Naoki Hoshino, Masanobu Yanase, Taisuke Ichiyasu, Kazuhiko Kuwahara, Hideki Kawai, Takashi Muramatsu, Hideki Ishii, Tetsuya Tsukamoto, Shin ichiro Morimoto, Hideo Izawa

Research output: Contribution to journalArticlepeer-review

Abstract

There have been few case reports on fatal outcomes in patients with acute myocarditis after mRNA coronavirus disease 2019 (COVID-19) vaccination. In most cases of myocarditis after mRNA COVID-19 vaccination, the myocarditis is mild, and the prognosis is good. Here we report an autopsy case of fulminant myocarditis following mRNA COVID-19 vaccination. Learning objective: The global distribution of the mRNA coronavirus disease 2019 vaccine requires consideration of appropriate treatment for postvaccination myocarditis. Eosinophil-mediated immunological injury to cardiomyocytes can be involved in the cause of fulminant inflammation from the pathological findings of postvaccination myocarditis.

Original languageEnglish
JournalJournal of Cardiology Cases
DOIs
Publication statusAccepted/In press - 2022

All Science Journal Classification (ASJC) codes

  • Cardiology and Cardiovascular Medicine

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