An EcoRI RFLP in human APC gene

Hiroki Kurahashi, Koji Takami, Ikuo Yana, Kenzo Akagi, Shintaro Okada, Isamu Nishisho

Research output: Contribution to journalArticlepeer-review

Abstract

A novel EcoRI-restriction fragment length polymorphism in the genomic sequence of the human adenomatous polyposis coli (APC) gene is described. This polymorphism in the APC gene would be very useful for examination of segregation of the mutated APC gene in the kindreds of familial adenomatous polyposis, and also for studying the loss of heterozygosity at the APC region in certain tumors.

Original languageEnglish
Pages (from-to)339-341
Number of pages3
JournalThe Japanese Journal of Human Genetics
Volume40
Issue number4
DOIs
Publication statusPublished - 12-1995
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Genetics(clinical)

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