Analysis of factors for predicting survival in soft-tissue sarcoma with metastatic disease at initial presentation

Tomoki Nakamura, Hirohisa Katagiri, Yoji Shido, Shunsuke Hamada, Kenji Yamada, Akihito Nagano, Satoshi Yamada, Satoshi Tsukushi, Daisuke Ishimura, Akihiko Matsumine, Akihiro Sudo, Yoshihiro Nishida

Research output: Contribution to journalArticlepeer-review

8 Citations (Scopus)

Abstract

Background/Aim: We aimed to confirm predictors of survival in soft-tissue sarcoma (STS) patients with metastatic disease at initial presentation in 9 Institutions under the Tokai Musculoskeletal Oncology Consortium. Patients and Methods: Between 2008 and 2013, 47 STS patients with metastatic disease at initial presentation were referred for treatment. The mean follow-up duration was 24 months. Results: The mean C-reactive protein (CRP) levels were 2.47 mg/dl. The mean hemoglobin and albumin levels were 13.1 g/dl and 4.1 g/dl, respectively. Hemoglobin and albumin levels were significantly correlated with CRP levels. In the multivariate analysis, age, CRP levels, and albumin levels were confirmed as independent prognostic factors for disease-specific survival (DSS). Conclusion: We suggest that the measurements of CRP and albumin levels are a useful method of identifying STS patients with metastasis at initial presentation that have poor prognosis.

Original languageEnglish
Pages (from-to)3137-3141
Number of pages5
JournalAnticancer research
Volume37
Issue number6
DOIs
Publication statusPublished - 06-2017

All Science Journal Classification (ASJC) codes

  • Oncology
  • Cancer Research

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