Analysis of factors for predicting survival in soft-tissue sarcoma with metastatic disease at initial presentation

Tomoki Nakamura; Hirohisa Katagiri; Yoji Shido; Shunsuke Hamada; Kenji Yamada; Akihito Nagano; Satoshi Yamada; Satoshi Tsukushi; Daisuke Ishimura; Akihiko Matsumine; Akihiro Sudo; Yoshihiro Nishida

doi:10.21873/anticanres.11671

Analysis of factors for predicting survival in soft-tissue sarcoma with metastatic disease at initial presentation

Tomoki Nakamura
, Hirohisa Katagiri
, Yoji Shido
, Shunsuke Hamada
, Kenji Yamada
, Akihito Nagano
, Satoshi Yamada
, Satoshi Tsukushi
, Daisuke Ishimura
, Akihiko Matsumine
, Akihiro Sudo
, Yoshihiro Nishida

Orthopedic Surgery

Research output: Contribution to journal › Article › peer-review

25 Citations (Scopus)

Abstract

Background/Aim: We aimed to confirm predictors of survival in soft-tissue sarcoma (STS) patients with metastatic disease at initial presentation in 9 Institutions under the Tokai Musculoskeletal Oncology Consortium. Patients and Methods: Between 2008 and 2013, 47 STS patients with metastatic disease at initial presentation were referred for treatment. The mean follow-up duration was 24 months. Results: The mean C-reactive protein (CRP) levels were 2.47 mg/dl. The mean hemoglobin and albumin levels were 13.1 g/dl and 4.1 g/dl, respectively. Hemoglobin and albumin levels were significantly correlated with CRP levels. In the multivariate analysis, age, CRP levels, and albumin levels were confirmed as independent prognostic factors for disease-specific survival (DSS). Conclusion: We suggest that the measurements of CRP and albumin levels are a useful method of identifying STS patients with metastasis at initial presentation that have poor prognosis.

Original language	English
Pages (from-to)	3137-3141
Number of pages	5
Journal	Anticancer research
Volume	37
Issue number	6
DOIs	https://doi.org/10.21873/anticanres.11671
Publication status	Published - 06-2017

All Science Journal Classification (ASJC) codes

Oncology
Cancer Research

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.21873/anticanres.11671

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title = "Analysis of factors for predicting survival in soft-tissue sarcoma with metastatic disease at initial presentation",

abstract = "Background/Aim: We aimed to confirm predictors of survival in soft-tissue sarcoma (STS) patients with metastatic disease at initial presentation in 9 Institutions under the Tokai Musculoskeletal Oncology Consortium. Patients and Methods: Between 2008 and 2013, 47 STS patients with metastatic disease at initial presentation were referred for treatment. The mean follow-up duration was 24 months. Results: The mean C-reactive protein (CRP) levels were 2.47 mg/dl. The mean hemoglobin and albumin levels were 13.1 g/dl and 4.1 g/dl, respectively. Hemoglobin and albumin levels were significantly correlated with CRP levels. In the multivariate analysis, age, CRP levels, and albumin levels were confirmed as independent prognostic factors for disease-specific survival (DSS). Conclusion: We suggest that the measurements of CRP and albumin levels are a useful method of identifying STS patients with metastasis at initial presentation that have poor prognosis.",

author = "Tomoki Nakamura and Hirohisa Katagiri and Yoji Shido and Shunsuke Hamada and Kenji Yamada and Akihito Nagano and Satoshi Yamada and Satoshi Tsukushi and Daisuke Ishimura and Akihiko Matsumine and Akihiro Sudo and Yoshihiro Nishida",

year = "2017",

month = jun,

doi = "10.21873/anticanres.11671",

language = "English",

volume = "37",

pages = "3137--3141",

journal = "Anticancer research",

issn = "0250-7005",

publisher = "International Institute of Anticancer Research",

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TY - JOUR

T1 - Analysis of factors for predicting survival in soft-tissue sarcoma with metastatic disease at initial presentation

AU - Nakamura, Tomoki

AU - Katagiri, Hirohisa

AU - Shido, Yoji

AU - Hamada, Shunsuke

AU - Yamada, Kenji

AU - Nagano, Akihito

AU - Yamada, Satoshi

AU - Tsukushi, Satoshi

AU - Ishimura, Daisuke

AU - Matsumine, Akihiko

AU - Sudo, Akihiro

AU - Nishida, Yoshihiro

PY - 2017/6

Y1 - 2017/6

N2 - Background/Aim: We aimed to confirm predictors of survival in soft-tissue sarcoma (STS) patients with metastatic disease at initial presentation in 9 Institutions under the Tokai Musculoskeletal Oncology Consortium. Patients and Methods: Between 2008 and 2013, 47 STS patients with metastatic disease at initial presentation were referred for treatment. The mean follow-up duration was 24 months. Results: The mean C-reactive protein (CRP) levels were 2.47 mg/dl. The mean hemoglobin and albumin levels were 13.1 g/dl and 4.1 g/dl, respectively. Hemoglobin and albumin levels were significantly correlated with CRP levels. In the multivariate analysis, age, CRP levels, and albumin levels were confirmed as independent prognostic factors for disease-specific survival (DSS). Conclusion: We suggest that the measurements of CRP and albumin levels are a useful method of identifying STS patients with metastasis at initial presentation that have poor prognosis.

AB - Background/Aim: We aimed to confirm predictors of survival in soft-tissue sarcoma (STS) patients with metastatic disease at initial presentation in 9 Institutions under the Tokai Musculoskeletal Oncology Consortium. Patients and Methods: Between 2008 and 2013, 47 STS patients with metastatic disease at initial presentation were referred for treatment. The mean follow-up duration was 24 months. Results: The mean C-reactive protein (CRP) levels were 2.47 mg/dl. The mean hemoglobin and albumin levels were 13.1 g/dl and 4.1 g/dl, respectively. Hemoglobin and albumin levels were significantly correlated with CRP levels. In the multivariate analysis, age, CRP levels, and albumin levels were confirmed as independent prognostic factors for disease-specific survival (DSS). Conclusion: We suggest that the measurements of CRP and albumin levels are a useful method of identifying STS patients with metastasis at initial presentation that have poor prognosis.

UR - https://www.scopus.com/pages/publications/85019751741

UR - https://www.scopus.com/pages/publications/85019751741#tab=citedBy

U2 - 10.21873/anticanres.11671

DO - 10.21873/anticanres.11671

M3 - Article

C2 - 28551655

AN - SCOPUS:85019751741

SN - 0250-7005

VL - 37

SP - 3137

EP - 3141

JO - Anticancer research

JF - Anticancer research

IS - 6

ER -

Analysis of factors for predicting survival in soft-tissue sarcoma with metastatic disease at initial presentation

Abstract

All Science Journal Classification (ASJC) codes

UN SDGs

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