Analysis of Musculoskeletal Systems and Their Diseases. Gene regulatory network in development and maintenance of skeletal muscle cells

Takahiko Sato, Shinichi Takeda

Research output: Contribution to journalArticle

Abstract

In this section, we describe about key upstream factors to lead to the activation, differentiation of skeletal muscle cells in the mouse and chick models, such as Pax3/Pax7 genes. They are involved in gene regulatory networks at various sites of skeletal muscle formation. And microRNAs intervene with emerging evidences for novel roles to regulate key factors in myogenesis. We discuss new myogenic insights into mechanisms underlying the transcriptional activity of these factors.

Original languageEnglish
Pages (from-to)1141-1146
Number of pages6
JournalClinical calcium
Volume25
Issue number8
Publication statusPublished - 01-08-2015
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Medicine(all)

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