Analysis of platelet production following liver transplantation using the immature platelet fraction (IPF) parameter

Akane Sakaguchi, Hideo Wada, Yasunori Abe, Hiroaki Tomatsu, Junji Nishioka, Yoshitaka Morishita, Shinichiro Okuni, Masanobu Usui, Shuji Isaji, Tsutomu Nobori

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4 Citations (Scopus)

Abstract

Although liver transplantation (LT) is frequently associated with thrombocytopenia, thrombopoiesis following LT remains to be evaluated. We analyzed platelet counts (PLT), immature Platelet Fraction (IPF), and thrombopoietin (TPO) in 8 patients with LT. PLT and IPF were measured using Sysmex XE-2100. TPO was measured with Human TPO ELISA Kit. In 7 of 8 patients with LT, IPF increased prior to the elevation of platelet counts. In 5 of 7 patients with increased IPF, TPO levels increased simultaneously with IPF, suggesting that IPF may reflect the production of platelets in patients with LT. IPF and TPO might be useful to monitor the platelet production in patients following LT.

Original languageEnglish
Pages (from-to)29-35
Number of pages7
JournalRinsho byori. The Japanese journal of clinical pathology
Volume56
Issue number1
Publication statusPublished - 01-2008
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Medicine(all)

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    Sakaguchi, A., Wada, H., Abe, Y., Tomatsu, H., Nishioka, J., Morishita, Y., Okuni, S., Usui, M., Isaji, S., & Nobori, T. (2008). Analysis of platelet production following liver transplantation using the immature platelet fraction (IPF) parameter. Rinsho byori. The Japanese journal of clinical pathology, 56(1), 29-35.