Analysis of platelet production following liver transplantation using the immature platelet fraction (IPF) parameter

Akane Sakaguchi; Hideo Wada; Yasunori Abe; Hiroaki Tomatsu; Junji Nishioka; Yoshitaka Morishita; Shinichiro Okuni; Masanobu Usui; Shuji Isaji; Tsutomu Nobori

Analysis of platelet production following liver transplantation using the immature platelet fraction (IPF) parameter

Akane Sakaguchi, Hideo Wada, Yasunori Abe, Hiroaki Tomatsu, Junji Nishioka, Yoshitaka Morishita, Shinichiro Okuni, Masanobu Usui, Shuji Isaji, Tsutomu Nobori

Research output: Contribution to journal › Review article › peer-review

4 Citations (Scopus)

Abstract

Although liver transplantation (LT) is frequently associated with thrombocytopenia, thrombopoiesis following LT remains to be evaluated. We analyzed platelet counts (PLT), immature Platelet Fraction (IPF), and thrombopoietin (TPO) in 8 patients with LT. PLT and IPF were measured using Sysmex XE-2100. TPO was measured with Human TPO ELISA Kit. In 7 of 8 patients with LT, IPF increased prior to the elevation of platelet counts. In 5 of 7 patients with increased IPF, TPO levels increased simultaneously with IPF, suggesting that IPF may reflect the production of platelets in patients with LT. IPF and TPO might be useful to monitor the platelet production in patients following LT.

Original language	English
Pages (from-to)	29-35
Number of pages	7
Journal	Rinsho byori. The Japanese journal of clinical pathology
Volume	56
Issue number	1
Publication status	Published - 01-2008
Externally published	Yes

All Science Journal Classification (ASJC) codes

General Medicine

Cite this

@article{eb1883c0ac094fa6bd234f34c6c29773,

title = "Analysis of platelet production following liver transplantation using the immature platelet fraction (IPF) parameter",

abstract = "Although liver transplantation (LT) is frequently associated with thrombocytopenia, thrombopoiesis following LT remains to be evaluated. We analyzed platelet counts (PLT), immature Platelet Fraction (IPF), and thrombopoietin (TPO) in 8 patients with LT. PLT and IPF were measured using Sysmex XE-2100. TPO was measured with Human TPO ELISA Kit. In 7 of 8 patients with LT, IPF increased prior to the elevation of platelet counts. In 5 of 7 patients with increased IPF, TPO levels increased simultaneously with IPF, suggesting that IPF may reflect the production of platelets in patients with LT. IPF and TPO might be useful to monitor the platelet production in patients following LT.",

author = "Akane Sakaguchi and Hideo Wada and Yasunori Abe and Hiroaki Tomatsu and Junji Nishioka and Yoshitaka Morishita and Shinichiro Okuni and Masanobu Usui and Shuji Isaji and Tsutomu Nobori",

year = "2008",

month = jan,

language = "English",

volume = "56",

pages = "29--35",

journal = "Rinsho byori. The Japanese journal of clinical pathology",

issn = "0047-1860",

publisher = "Nihon Rinsho Byori Gakkai",

number = "1",

}

TY - JOUR

T1 - Analysis of platelet production following liver transplantation using the immature platelet fraction (IPF) parameter

AU - Sakaguchi, Akane

AU - Wada, Hideo

AU - Abe, Yasunori

AU - Tomatsu, Hiroaki

AU - Nishioka, Junji

AU - Morishita, Yoshitaka

AU - Okuni, Shinichiro

AU - Usui, Masanobu

AU - Isaji, Shuji

AU - Nobori, Tsutomu

PY - 2008/1

Y1 - 2008/1

N2 - Although liver transplantation (LT) is frequently associated with thrombocytopenia, thrombopoiesis following LT remains to be evaluated. We analyzed platelet counts (PLT), immature Platelet Fraction (IPF), and thrombopoietin (TPO) in 8 patients with LT. PLT and IPF were measured using Sysmex XE-2100. TPO was measured with Human TPO ELISA Kit. In 7 of 8 patients with LT, IPF increased prior to the elevation of platelet counts. In 5 of 7 patients with increased IPF, TPO levels increased simultaneously with IPF, suggesting that IPF may reflect the production of platelets in patients with LT. IPF and TPO might be useful to monitor the platelet production in patients following LT.

AB - Although liver transplantation (LT) is frequently associated with thrombocytopenia, thrombopoiesis following LT remains to be evaluated. We analyzed platelet counts (PLT), immature Platelet Fraction (IPF), and thrombopoietin (TPO) in 8 patients with LT. PLT and IPF were measured using Sysmex XE-2100. TPO was measured with Human TPO ELISA Kit. In 7 of 8 patients with LT, IPF increased prior to the elevation of platelet counts. In 5 of 7 patients with increased IPF, TPO levels increased simultaneously with IPF, suggesting that IPF may reflect the production of platelets in patients with LT. IPF and TPO might be useful to monitor the platelet production in patients following LT.

UR - http://www.scopus.com/inward/record.url?scp=41949142629&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=41949142629&partnerID=8YFLogxK

M3 - Review article

C2 - 18320661

AN - SCOPUS:41949142629

SN - 0047-1860

VL - 56

SP - 29

EP - 35

JO - Rinsho byori. The Japanese journal of clinical pathology

JF - Rinsho byori. The Japanese journal of clinical pathology

IS - 1

ER -

Analysis of platelet production following liver transplantation using the immature platelet fraction (IPF) parameter

Abstract

All Science Journal Classification (ASJC) codes

Other files and links

Fingerprint

Cite this