Analyzing Effect of Waterclefts on Visual Functions Via Optical Simulations

Yusuke Seki, Takushi Kawamorita, Naoki Yamamoto, Takashi Tanigawa, Norihiro Mita, Natsuko Hatsusaka, Eri Kubo, Hiroshi Sasaki

Research output: Contribution to journalArticlepeer-review

1 Citation (Scopus)


PURPOSE. To investigate the impact of the size and location of waterclefts (WC), which are one of several cataract subtypes, on visual function by optical simulation analysis. METHODS. An optical simulation software (CODE V) was used to develop a schematic eye model and several sizes of WC central and peripheral types that were located below the anterior and posterior subcapsules of the crystalline lens, and analyses of refraction, higher-order aberrations (HOA), and the modulation transfer function (MTF) were performed. RESULTS. An increase in the WC size increased the refraction and HOA and decreased the MTF. The impact of the WC below the posterior subcapsule on the visual function was more enhanced than that below the anterior subcapsule. Large WC demonstrated a remarkable hyperopic shift in refractive power as well as an increase in HOA. The MTF decreased slightly with increasing WC size at a spatial frequency of 20 cycles/mm, and it decreased remarkably at 60 cycles/mm. CONCLUSIONS. The impact on the visual function increased with increasing WC size. It was revealed that eyes with WC below the posterior subcapsule are more hyperopic than those with WC below the anterior subcapsule, and the former have a higher HOA and lower MTF than the latter.

Original languageEnglish
Article number22
JournalInvestigative Ophthalmology and Visual Science
Issue number2
Publication statusPublished - 02-2022

All Science Journal Classification (ASJC) codes

  • Ophthalmology
  • Sensory Systems
  • Cellular and Molecular Neuroscience


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