Abstract
The aim of the present study was to investigate whether anodal transcranial direct-current stimulation (tDCS) of lower-limb primary motor cortex (M1) could increase cortical excitability when reference electrodes were placed at extracephalic positions. Ten healthy volunteers participated in this study. Anodal electrodes were placed over the left lower-limb M1, whereas reference electrodes were placed on the contralateral forehead (cephalic condition) or contralateral upper arm (extracephalic condition). Motor evoked potentials (MEPs) were recorded as a measure of cortical excitability before and after tDCS (2 mA, 10 minutes). Compared with a sham condition, MEPs significantly increased for both cephalic and extracephalic conditions, and this increase was maintained for approximately 60 minutes after stimulation. No side effects were reported. We conclude that tDCS over lower-limb M1 in conjunction with extracephalic reference electrodes can increase cortical excitability without any side effects.
| Original language | English |
|---|---|
| Title of host publication | Biosystems and Biorobotics |
| Publisher | Springer International Publishing |
| Pages | 829-834 |
| Number of pages | 6 |
| DOIs | |
| Publication status | Published - 01-01-2013 |
| Externally published | Yes |
Publication series
| Name | Biosystems and Biorobotics |
|---|---|
| Volume | 1 |
| ISSN (Print) | 2195-3562 |
| ISSN (Electronic) | 2195-3570 |
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All Science Journal Classification (ASJC) codes
- Biomedical Engineering
- Mechanical Engineering
- Artificial Intelligence
Cite this
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Anodal transcranial direct current stimulation over the lower limb motor cortex increases the cortical excitability with extracephalic reference electrodes. / Tatemoto, Tsuyoshi; Yamaguchi, Tomofumi; Otaka, Yohei; Kondo, Kunitsugu; Tanaka, Satoshi.
Biosystems and Biorobotics. Springer International Publishing, 2013. p. 829-834 (Biosystems and Biorobotics; Vol. 1).Research output: Chapter in Book/Report/Conference proceeding › Chapter
TY - CHAP
T1 - Anodal transcranial direct current stimulation over the lower limb motor cortex increases the cortical excitability with extracephalic reference electrodes
AU - Tatemoto, Tsuyoshi
AU - Yamaguchi, Tomofumi
AU - Otaka, Yohei
AU - Kondo, Kunitsugu
AU - Tanaka, Satoshi
PY - 2013/1/1
Y1 - 2013/1/1
N2 - The aim of the present study was to investigate whether anodal transcranial direct-current stimulation (tDCS) of lower-limb primary motor cortex (M1) could increase cortical excitability when reference electrodes were placed at extracephalic positions. Ten healthy volunteers participated in this study. Anodal electrodes were placed over the left lower-limb M1, whereas reference electrodes were placed on the contralateral forehead (cephalic condition) or contralateral upper arm (extracephalic condition). Motor evoked potentials (MEPs) were recorded as a measure of cortical excitability before and after tDCS (2 mA, 10 minutes). Compared with a sham condition, MEPs significantly increased for both cephalic and extracephalic conditions, and this increase was maintained for approximately 60 minutes after stimulation. No side effects were reported. We conclude that tDCS over lower-limb M1 in conjunction with extracephalic reference electrodes can increase cortical excitability without any side effects.
AB - The aim of the present study was to investigate whether anodal transcranial direct-current stimulation (tDCS) of lower-limb primary motor cortex (M1) could increase cortical excitability when reference electrodes were placed at extracephalic positions. Ten healthy volunteers participated in this study. Anodal electrodes were placed over the left lower-limb M1, whereas reference electrodes were placed on the contralateral forehead (cephalic condition) or contralateral upper arm (extracephalic condition). Motor evoked potentials (MEPs) were recorded as a measure of cortical excitability before and after tDCS (2 mA, 10 minutes). Compared with a sham condition, MEPs significantly increased for both cephalic and extracephalic conditions, and this increase was maintained for approximately 60 minutes after stimulation. No side effects were reported. We conclude that tDCS over lower-limb M1 in conjunction with extracephalic reference electrodes can increase cortical excitability without any side effects.
UR - http://www.scopus.com/inward/record.url?scp=85018400892&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85018400892&partnerID=8YFLogxK
U2 - 10.1007/978-3-642-34546-3_135
DO - 10.1007/978-3-642-34546-3_135
M3 - Chapter
AN - SCOPUS:85018400892
T3 - Biosystems and Biorobotics
SP - 829
EP - 834
BT - Biosystems and Biorobotics
PB - Springer International Publishing
ER -