Anti-neutral glycolipids antibody-positive combined central and peripheral demyelination mimicking encephalomyeloradiculoneuropathy phenotype

Kazuyuki Saito, Shuta Toru, Sayuri Shima, Tatsuro Mutoh

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

We herein report the first combined central and peripheral demyelination (CCPD) case originally diagnosed as multifocal acquired demyelinating sensory and motor neuropathy followed by CNS impairments with a long lag time (160 days after first attack). The anti-neutral glycolipids antibodies, especially anti-lactosylceramide antibodies but not anti-NF155 antibodies typical for CCPD were detected in the acute phase of sera and cerebrospinal fluid (CSF) and disappeared in the recovery phase. This case strongly illustrated the significance of examining anti-neutral glycolipids antibodies in future anti-NF 155 antibodies-negative CCPD cases.

Original languageEnglish
Pages (from-to)90-92
Number of pages3
JournalClinical Neurology and Neurosurgery
Volume172
DOIs
Publication statusPublished - 09-2018

All Science Journal Classification (ASJC) codes

  • Surgery
  • Clinical Neurology

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