TY - JOUR
T1 - Anxiety and behavioral changes in Japanese patients with inflammatory bowel disease due to COVID-19 pandemic
T2 - a national survey
AU - Nakase, Hiroshi
AU - Wagatsuma, Kohei
AU - Nojima, Masanori
AU - Matsumoto, Takayuki
AU - Matsuura, Minoru
AU - Iijima, Hideki
AU - Matsuoka, Katsuyoshi
AU - Ohmiya, Naoki
AU - Ishihara, Shunji
AU - Hirai, Fumihito
AU - Takeuchi, Ken
AU - Tamura, Satoshi
AU - Kinjo, Fukunori
AU - Ueno, Nobuhiro
AU - Naganuma, Makoto
AU - Watanabe, Kenji
AU - Moroi, Rintaro
AU - Nishimata, Nobuaki
AU - Motoya, Satoshi
AU - Kurahara, Koichi
AU - Takahashi, Sakuma
AU - Maemoto, Atsuo
AU - Sakuraba, Hirotake
AU - Saruta, Masayuki
AU - Tominaga, Keiichi
AU - Hisabe, Takashi
AU - Tanaka, Hiroki
AU - Terai, Shuji
AU - Hiraoka, Sakiko
AU - Takedomi, Hironobu
AU - Narimatsu, Kazuyuki
AU - Endo, Katsuya
AU - Nakamura, Masanao
AU - Hisamatsu, Tadakazu
N1 - Funding Information:
The authors are grateful to all The Japan COVID-19 Survey and the Questionnaire for Inflammatory Bowel Disease (J-DESIRE) Group: Sae Ohwada (Sapporo Medical University School of Medicine), Takehiro Hirano (Sapporo Medical University School of Medicine), Yoshihiro Yokoyama (Sapporo Medical University School of Medicine), Tsukasa Yamakawa (Sapporo Medical University School of Medicine), Yuki Hayashi (Sapporo Medical University School of Medicine) Tadashi Ichimiya (Sapporo Medical University School of Medicine), Tomoe Kazama (Sapporo Medical University School of Medicine), Daisuke Hirayama (Sapporo Medical University School of Medicine), Ayuko Hazumi (Sapporo Medical University Hospital), Ayumi Kadoya (Sapporo Medical University Hospital), Saki Asakura (Sapporo Medical University Hospital), Naomi Ebisawa (Sapporo Medical University Hospital), Shunichi Yanai (Iwate Medical University), Daisuke Saito (Kyorin University School of Medicine), Shinichiro Shinzaki (Osaka University Graduate School of Medicine), Akihiro Yamada (Toho University Sakura Medical Center), Mitsuo Nagasaka (Fujita Health University School of Medicine), Kousaku Kawashima (Shimane University Faculty of Medicine), Nobuaki Kuno (Fukuoka University), Yoshihiro Shimoyama (Tsujinaka Hospital Kashiwanoha), Ken Sugimoto (Hamamatsu University School of Medicine), Nobufumi Uchima (Urasoe General Hospital), Mikihiro Fujiya (Asahikawa Medical University), Norimasa Fukata (Kansai Medical University), Yoko Yokoyama (Hyogo College of Medicine), Atsushi Masamune (Tohoku University Hospital), Yukinori Sameshima (Sameshima Hospital), Ryosuke Kiyomori (Matsuyama Red Cross Hospital), Tomoki Inaba (Kagawa Prefectural Central Hospital), Takahiro Ito (Sapporo Higashi Tokushukai Hospital), Hiroto Hiraga (Hirosaki University Graduate School of Medicine), Takahiko Toyonaga (The Jikei University School of Medicine), Takanao Tanaka (Dokkyo Medical University), Akihiro Koga (Fukuoka University Chikushi Hospital), Masanao Nasuno (Sapporo IBD Clinic), Junji Yokoyama (Niigata University), Eriko Yasutomi (Okayama University Graduate School of Medicine), Motohiro Esaki (Saga University), Ryota Hokari (National Defense Medical College) Yuki Yoshino(Tohoku Medical and Pharmaceutical University).
Funding Information:
This work was supported by the Health and Labour Sciences Research Grants for research on intractable diseases from the Ministry of Health, Labour and Welfare (MHLW) of Japan (Investigation and Research for intractable Inflammatory Bowel Disease) (Grant Number 20FC1037), and by MHLW Research Program on Emerging and Reemerging Infections Diseases (Grant Number JPMH21HA2011).
Publisher Copyright:
© 2023, The Author(s).
PY - 2023/3
Y1 - 2023/3
N2 - Background: Given the increasing health concerns for patients with inflammatory bowel disease (IBD), amidst the COVID-19 pandemic, we investigated the impact of the pandemic on the anxiety and behavioral changes in Japanese patients with IBD. Methods: We analyzed 3032 questionnaires from patients with IBD, aged 16 years or older visiting 30 hospitals and 1 clinic between March 2020 and June 2021. The primary outcome was the score of the anxiety experienced by patients with IBD during the pandemic. Results: Participants reported a median age of 44 years; 43.3% of the patients were women. Moreover, 60.6% and 39.4% were diagnosed with ulcerative colitis and Crohn’s disease, respectively, with a median disease duration of 10 years. Participants indicated an average of disease-related anxiety score of 5.1 ± 2.5 on a ten-point scale, with a tendency to increase, 1 month after the number of infected persons per population increased. The top three causes for anxiety were the risk of contracting COVID-19 during hospital visits, SARS-CoV-2 infection due to IBD, and infection by IBD medication. Factors associated with anxiety were gender (women), being a homemaker, hospital visit timings, mode of transportation (train), use of immunosuppressive drugs, and nutritional therapy. Most patients continued attending their scheduled hospital visits, taking their medications, experienced the need for a family doctor, and sought guidance and information regarding COVID-19 from primary doctors, television, and Internet news. Conclusions: Patients with IBD experienced moderate disease-related anxiety due to the pandemic and should be proactively informed about infectious diseases to relieve their anxiety.
AB - Background: Given the increasing health concerns for patients with inflammatory bowel disease (IBD), amidst the COVID-19 pandemic, we investigated the impact of the pandemic on the anxiety and behavioral changes in Japanese patients with IBD. Methods: We analyzed 3032 questionnaires from patients with IBD, aged 16 years or older visiting 30 hospitals and 1 clinic between March 2020 and June 2021. The primary outcome was the score of the anxiety experienced by patients with IBD during the pandemic. Results: Participants reported a median age of 44 years; 43.3% of the patients were women. Moreover, 60.6% and 39.4% were diagnosed with ulcerative colitis and Crohn’s disease, respectively, with a median disease duration of 10 years. Participants indicated an average of disease-related anxiety score of 5.1 ± 2.5 on a ten-point scale, with a tendency to increase, 1 month after the number of infected persons per population increased. The top three causes for anxiety were the risk of contracting COVID-19 during hospital visits, SARS-CoV-2 infection due to IBD, and infection by IBD medication. Factors associated with anxiety were gender (women), being a homemaker, hospital visit timings, mode of transportation (train), use of immunosuppressive drugs, and nutritional therapy. Most patients continued attending their scheduled hospital visits, taking their medications, experienced the need for a family doctor, and sought guidance and information regarding COVID-19 from primary doctors, television, and Internet news. Conclusions: Patients with IBD experienced moderate disease-related anxiety due to the pandemic and should be proactively informed about infectious diseases to relieve their anxiety.
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U2 - 10.1007/s00535-022-01949-6
DO - 10.1007/s00535-022-01949-6
M3 - Article
C2 - 36607399
AN - SCOPUS:85145736660
SN - 0944-1174
VL - 58
SP - 205
EP - 216
JO - Journal of Gastroenterology
JF - Journal of Gastroenterology
IS - 3
ER -