Aspergillus meningitis in a patient with chronic lymphocytic leukemia

Takahiro Matsuo; Nobuyoshi Mori; Aki Sakurai; Keiichi Furukawa

doi:10.1016/j.jiac.2020.01.012

Aspergillus meningitis in a patient with chronic lymphocytic leukemia

Takahiro Matsuo
, Nobuyoshi Mori
, Aki Sakurai
, Keiichi Furukawa

Research output: Contribution to journal › Article › peer-review

2 Citations (Scopus)

Abstract

Central nervous system aspergillosis is relatively rare and difficult to diagnose. Here, we report a case of 90-year-old man with chronic lymphocytic leukemia who presented with a month-long gradually worsening headache followed by 3 days of low-grade fever associated with altered mental status. Aspergillus meningitis diagnosed using Aspergillus galactomannan antigen in the cerebrospinal fluid and treated with voriconazole. Delayed diagnosis and treatment of Aspergillus meningitis is typically associated with high mortality; therefore, it is imperative to include this disease in the differential diagnoses of subacute meningitis.

Original language	English
Pages (from-to)	622-624
Number of pages	3
Journal	Journal of Infection and Chemotherapy
Volume	26
Issue number	6
DOIs	https://doi.org/10.1016/j.jiac.2020.01.012
Publication status	Published - 06-2020
Externally published	Yes

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

All Science Journal Classification (ASJC) codes

Microbiology (medical)
Pharmacology (medical)
Infectious Diseases

Access to Document

10.1016/j.jiac.2020.01.012

Cite this

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title = "Aspergillus meningitis in a patient with chronic lymphocytic leukemia",

abstract = "Central nervous system aspergillosis is relatively rare and difficult to diagnose. Here, we report a case of 90-year-old man with chronic lymphocytic leukemia who presented with a month-long gradually worsening headache followed by 3 days of low-grade fever associated with altered mental status. Aspergillus meningitis diagnosed using Aspergillus galactomannan antigen in the cerebrospinal fluid and treated with voriconazole. Delayed diagnosis and treatment of Aspergillus meningitis is typically associated with high mortality; therefore, it is imperative to include this disease in the differential diagnoses of subacute meningitis.",

author = "Takahiro Matsuo and Nobuyoshi Mori and Aki Sakurai and Keiichi Furukawa",

note = "Publisher Copyright: {\textcopyright} 2020 Japanese Society of Chemotherapy and The Japanese Association for Infectious Diseases",

year = "2020",

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doi = "10.1016/j.jiac.2020.01.012",

language = "English",

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TY - JOUR

T1 - Aspergillus meningitis in a patient with chronic lymphocytic leukemia

AU - Matsuo, Takahiro

AU - Mori, Nobuyoshi

AU - Sakurai, Aki

AU - Furukawa, Keiichi

PY - 2020/6

Y1 - 2020/6

N2 - Central nervous system aspergillosis is relatively rare and difficult to diagnose. Here, we report a case of 90-year-old man with chronic lymphocytic leukemia who presented with a month-long gradually worsening headache followed by 3 days of low-grade fever associated with altered mental status. Aspergillus meningitis diagnosed using Aspergillus galactomannan antigen in the cerebrospinal fluid and treated with voriconazole. Delayed diagnosis and treatment of Aspergillus meningitis is typically associated with high mortality; therefore, it is imperative to include this disease in the differential diagnoses of subacute meningitis.

AB - Central nervous system aspergillosis is relatively rare and difficult to diagnose. Here, we report a case of 90-year-old man with chronic lymphocytic leukemia who presented with a month-long gradually worsening headache followed by 3 days of low-grade fever associated with altered mental status. Aspergillus meningitis diagnosed using Aspergillus galactomannan antigen in the cerebrospinal fluid and treated with voriconazole. Delayed diagnosis and treatment of Aspergillus meningitis is typically associated with high mortality; therefore, it is imperative to include this disease in the differential diagnoses of subacute meningitis.

UR - https://www.scopus.com/pages/publications/85080953152

UR - https://www.scopus.com/pages/publications/85080953152#tab=citedBy

U2 - 10.1016/j.jiac.2020.01.012

DO - 10.1016/j.jiac.2020.01.012

M3 - Article

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AN - SCOPUS:85080953152

SN - 1341-321X

VL - 26

SP - 622

EP - 624

JO - Journal of Infection and Chemotherapy

JF - Journal of Infection and Chemotherapy

IS - 6

ER -

Aspergillus meningitis in a patient with chronic lymphocytic leukemia

Abstract

UN SDGs

All Science Journal Classification (ASJC) codes

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