Assessment of in-stent restenosis using high-definition computed tomography with a new gemstone detector

Takuma Tsuda, Hideki Ishii, Satoshi Ichimiya, Masaaki Kanashiro, Jyunji Watanabe, Mikito Takefuji, Toru Aoyama, Susumu Suzuki, Akihito Tanaka, Tatsuaki Matsubara, Toyoaki Murohara

Research output: Contribution to journalArticle

Abstract

Background: Until now, there have been few reports on the accuracy of in-stent restenosis (ISR) detection using high-definition computed tomography (HDCT). The purpose of this study was to assess ISR using HDCT with a new gemstone detector and to examine the diagnostic accuracy compared with invasive coronary angiography. Methods and Results: We evaluated 162 consecutive patients with 316 stents and the image quality (IQ) scores used to assess ISR, and analyzed whether stent strut thickness and diameter affected IQ score and assessability. In the 316 stents, 278 were diagnosed as assessable with HDCT (88.0%). IQ score for stent diameter ≥3 mm was significantly higher than that for stent diameter <3 mm, for stents with both thick struts ≥140 μm in thickness (mean IQ: 2.04±0.97 vs. 2.83±1.06, P<0.001) and thin struts <140 μm (mean IQ: 1.92±0.87 vs. 2.64±0.96, P=0.01). Assessability for stent diameter ≥3 mm was significantly higher than that for stent diameter <3 mm only for stents with thick struts (92.8% vs. 76.1%, P<0.001). Stent strut thickness, however, was not statistically significantly associated with either IQ score or assessability. Conclusions: In-stent lumens have high HDCT assessability, and HDCT is useful to evaluate thick-strut stents with diameter <3 mm.

Original languageEnglish
Pages (from-to)1542-1548
Number of pages7
JournalCirculation Journal
Volume79
Issue number7
DOIs
Publication statusPublished - 09-06-2015
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Cardiology and Cardiovascular Medicine

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    Tsuda, T., Ishii, H., Ichimiya, S., Kanashiro, M., Watanabe, J., Takefuji, M., Aoyama, T., Suzuki, S., Tanaka, A., Matsubara, T., & Murohara, T. (2015). Assessment of in-stent restenosis using high-definition computed tomography with a new gemstone detector. Circulation Journal, 79(7), 1542-1548. https://doi.org/10.1253/circj.CJ-14-1344